| Comments |
Population: Caucasian.
Characteristics: This cell line is a knock-out for a transcript (Ensembl ENST00000510619) from a non-coding RNA gene (Ensembl ENSG00000251194) not yet in HGNC.
Doubling time: 48-72 hours (Hysigen=CGKO-M2632).
Derived from site: Metastatic; Brain; UBERON=UBERON_0000955. |
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| Sequence variations |
- Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Asp84Tyr (c.250G>T) (p.Arg98Leu, c.293G>T); ClinVar=VCV000376306; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:9884; RB1; Simple; p.Lys715Ter (c.2143A>T); ClinVar=VCV001786615; Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11389; STK11; Simple; p.Lys178fs*86 (c.532_536delAAGCC); Zygosity=Homozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro223Leu (c.668C>T); ClinVar=VCV000234214; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val274Phe (c.820G>T); ClinVar=VCV000376674; Zygosity=Heterozygous (from parent cell line).
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| Disease |
Prostate carcinoma (NCIt: C4863) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_0105 (DU145) |
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| Sex of cell |
Male |
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| Age at sampling |
69Y |
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| Category |
Cancer cell line |
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| Entry history |
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| Entry creation | 10-Sep-2024 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 2 |
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