Cellosaurus cell line ICC11 (CVCL

Cellosaurus ICC11 (CVCL_E4KQ)

Entry history
Cell line name	ICC11
Accession	CVCL_E4KQ
Resource Identification Initiative	To cite this cell line use: ICC11 (RRID:CVCL_E4KQ)
Comments	Part of: Biliary tract cancer cell line atlas. Population: African American.
Sequence variations	Gene fusion; HGNC; HGNC:3689; FGFR2 + HGNC; HGNC:8923; PHGDH; Name(s)=FGFR2-PHGDH (PubMed=39026794). Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gln219Ter (c.655C>T); ClinVar=VCV002630888; Zygosity=Unspecified (PubMed=39026794). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu35Cysfs*9 (c.102delC); ClinVar=VCV001072141; Zygosity=Unspecified (PubMed=39026794).
Disease	Intrahepatic cholangiocarcinoma (NCIt: C35417) Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_A1VB ! ICC10 CVCL_A1UZ ! ICC10-6 CVCL_A1VA ! ICC10-8
Sex of cell	Male
Category	Cancer cell line
Publications	PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448 Vindhya Vijay, Negin Karisani, Lei Shi, Yu-Han Hung, Phuong Vu, Prabhat Kattel, Lauren Kenney, Joshua Merritt, Ramzi Adil, Qi-Biao Wu, Yuan-Li Zhen ...Show all 39 authors... , Robert Morris, Johannes Kreuzer, Meena Kathiresan, Xcanda Ixchel Herrera Lopez, Haley Ellis, Ilaria G. Gritti, Lilian Lecorgne, Ines Farag, Alexandra Popa, William Shen, Hiroyuki Kato, Qin Xu, Eranga Roshan Balasooriya, Meng-Ju Wu, Saireudee Chaturantabut, Robin Kate Kelley, James Mark Cleary, Michael Scott Lawrence, David E. Root, Cyril Henri Benes, Vikram Deshpande, Dejan Juric, William Raj Sellers, Cristina Rosa Ferrone, Wilhelm Haas, Francisca Vazquez, Gad Getz, Nabeel M. Bardeesy; Show fewer authors Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets. bioRxiv 2024:07.04.601970-07.04.601970(2024)
Entry creation	19-Dec-2024
Last entry update	10-Apr-2025
Version number	2