Cellosaurus cell line ICC10 (CVCL

Cellosaurus ICC10 (CVCL_A1VB)

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Cell line name

ICC10

Accession

CVCL_A1VB

Resource Identification Initiative

To cite this cell line use: ICC10 (RRID:CVCL_A1VB)

Comments

Part of: Biliary tract cancer cell line atlas.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: African American.

Sequence variations

Gene fusion; HGNC; HGNC:3689; FGFR2 + HGNC; HGNC:8923; PHGDH; Name(s)=FGFR2-PHGDH (DepMap=ACH-001834; PubMed=39026794).
Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Gln219Ter (c.655C>T); ClinVar=VCV002630888; Zygosity=Unspecified (DepMap=ACH-001834; PubMed=39026794).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu35Cysfs*9 (c.102delC); ClinVar=VCV001072141; Zygosity=Unspecified (DepMap=ACH-001834; PubMed=39026794).

Disease

Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Originate from same individual

CVCL_A1UZ ! ICC10-6
CVCL_A1VA ! ICC10-8
CVCL_E4KQ ! ICC11

Sex of cell

Male

Category

Cancer cell line

STR profile

Source(s): DepMap=ACH-001834

Markers:

Amelogenin	X
CSF1PO	7,10
D3S1358	14,17
D5S818	12
D7S820	8,13
D8S1179	14,16
D13S317	8
D16S539	11,13
D18S51	12,17
D21S11	31.2
FGA	22
Penta D	9
Penta E	12
TH01	6,7
TPOX	8,11
vWA	16,18

Publications

PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448
Vindhya Vijay, Negin Karisani, Lei Shi, Yu-Han Hung, Phuong Vu, Prabhat Kattel, Lauren Kenney, Joshua Merritt, Ramzi Adil, Qi-Biao Wu, Yuan-Li Zhen ...Show all 39 authors... , Robert Morris, Johannes Kreuzer, Meena Kathiresan, Xcanda Ixchel Herrera Lopez, Haley Ellis, Ilaria G. Gritti, Lilian Lecorgne, Ines Farag, Alexandra Popa, William Shen, Hiroyuki Kato, Qin Xu, Eranga Roshan Balasooriya, Meng-Ju Wu, Saireudee Chaturantabut, Robin Kate Kelley, James Mark Cleary, Michael Scott Lawrence, David E. Root, Cyril Henri Benes, Vikram Deshpande, Dejan Juric, William Raj Sellers, Cristina Rosa Ferrone, Wilhelm Haas, Francisca Vazquez, Gad Getz, Nabeel M. Bardeesy; Show fewer authors
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
bioRxiv 2024:07.04.601970-07.04.601970(2024)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_A1VB
DepMap; ACH-001834

Encyclopedic resources

Wikidata; Q105509582

Entry history

Entry creation

12-Jan-2021

Last entry update

10-Apr-2025

Version number