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Cellosaurus CHO-DXB11 5E27 (CVCL_E4IB)

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Cell line name CHO-DXB11 5E27
Synonyms 5E27
Accession CVCL_E4IB
Resource Identification Initiative To cite this cell line use: CHO-DXB11 5E27 (RRID:CVCL_E4IB)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6019; IL6R (Note=With p.Phe345_Arg468del = sIL-6R).
Genetic integration: Method=Transfection; Gene=MGI; MGI:94890; Dhfr.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_1977 (CHO-DXB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=2292596; DOI=10.1093/oxfordjournals.jbchem.a123261
Kiyoshi Yasukawa, Takashi Saito, Takeshi Fukunaga, Yasuo Sekimori, Yasuo Koishihara, Hiroyasu Fukui, Yoshiyuki Ohsugi, Tadashi Matsuda, Hideo Yawata, Toshio Hirano, Tetsuya Taga, Tadamitsu Kishimoto;
Purification and characterization of soluble human IL-6 receptor expressed in CHO cells.
J. Biochem. 108:673-676(1990)

Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1