| Cell line name |
PC9/3-2 |
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| Accession |
CVCL_E4DF |
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| Resource Identification Initiative |
To cite this cell line use: PC9/3-2 (RRID:CVCL_E4DF) |
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| Comments |
Population: Chinese; Han and Japanese.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029. |
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| Sequence variations |
- Mutation; HGNC; HGNC:3236; EGFR; Simple; p.Glu746_Ala750del (c.2235_2249del15); ClinVar=VCV000163343; Zygosity=Unspecified (from parent cell line).
- Mutation; HGNC; HGNC:3236; EGFR; Simple_edited; p.Thr790Met (c.2369C>T); ClinVar=VCV000016613; Zygosity=Heterozygous; Note=By CRISPR/Cas9 (PubMed=28422737).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
|
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| Disease |
Lung adenocarcinoma (NCIt: C3512) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_B260 (PC-9) |
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| Sex of cell |
Male |
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| Age at sampling |
45Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=28422737; DOI=10.18632/oncotarget.16752; PMCID=PMC5482658
Mi-Young Park, Min Hee Jung, Eun Young Eo, Seokjoong Kim, Sang Hoon Lee, Yeon Joo Lee, Jong Sun Park, Young Jae Cho, Jin Haeng Chung, Cheol Hyeon Kim, Ho Il Yoon ...Show all 13 authors... , Jae Ho Lee, Choon-Taek Lee; Show fewer authors
Generation of lung cancer cell lines harboring EGFR T790M mutation by CRISPR/Cas9-mediated genome editing.
Oncotarget 8:36331-36338(2017) |
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| Entry history |
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| Entry creation | 19-Dec-2024 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 1 |
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