Cellosaurus cell line EYQ2-20 (CVCL

Cellosaurus EYQ2-20 (CVCL_E4CE)

Entry history
Cell line name	EYQ2-20
Accession	CVCL_E4CE
Resource Identification Initiative	To cite this cell line use: EYQ2-20 (RRID:CVCL_E4CE)
Comments	Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:14294; SHANK3 (Note=1 of 2 alleles). Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_9773 (WA09)
Sex of cell	Female
Age at sampling	Blastocyst stage
Category	Embryonic stem cell
Publications	PubMed=33558651; DOI=10.1038/s41380-021-01023-2; PMCID=PMC8349370 Simone Chiola, Kandy L. Napan, Yue-Qi Wang, Roman M. Lazarenko, Celeste J. Armstrong, Jun Cui, Aleksandr Shcheglovitov; Defective AMPA-mediated synaptic transmission and morphology in human neurons with hemizygous SHANK3 deletion engrafted in mouse prefrontal cortex. Mol. Psychiatry 26:4670-4686(2021) PubMed=36202854; DOI=10.1038/s41467-022-33364-z; PMCID=PMC9537523 Yue-Qi Wang, Simone Chiola, Guang Yang, Chad Russell, Celeste J. Armstrong, Yuan-Yuan Wu, Jay G. Spampanato, Paisley Tarboton, H.M. Arif Ullah, Nicolas U. Edgar, Amelia N. Chang ...Show all 19 authors... , David A. Harmin, Vittoria Dickinson Bocchi, Elena Vezzoli, Dario Besusso, Jun Cui, Elena Cattaneo, Jan Kubanek, Aleksandr Shcheglovitov; Show fewer authors Modeling human telencephalic development and autism-associated SHANK3 deficiency using organoids generated from single neural rosettes. Nat. Commun. 13:5688.1-5688.25(2022)
Entry creation	19-Dec-2024
Last entry update	19-Dec-2024
Version number	1