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Cellosaurus (CVCL_E4B3)

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Comments Part of: ENCODE project common cell types; tier 3.
Part of: Human Protein Atlas, Cell Atlas panel.
Population: Caucasian.
Senescence: Senesces at 72 PDL. Has a long lifespan in comparison with other normal human fibroblast cell lines (ATCC=CRL-2522).
Omics: Genomics; ChIP-seq; CTCF.
Omics: Genomics; ChIP-seq; H3K27me3.
Omics: Genomics; ChIP-seq; H3K36me3.
Omics: Genomics; ChIP-seq; H3K4me3.
Omics: Genomics; DNA methylation analysis.
Omics: Proteomics; Expression; Large antibody panel staining analysis.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling <1M
Category Finite cell line
STR profile Source(s): ATCC=CRL-2522; CLS=305222; PubMed=29444910

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133816,20
D3S135814,16
D5S81812
D7S82011,12
D8S11799,11
D13S3178,9
D16S5399,13
D18S5117,19
D19S43314
D21S1129
FGA22,23
Penta D12,13
Penta E7,17
TH017,8
TPOX10,11
vWA16,18

Run an STR similarity search on this cell line
Web pages Info; ENCODE; -; http://genome.ucsc.edu/ENCODE/protocols/cell/human/BJ_Stam_protocol.pdf
Info; HPA; -; https://www.proteinatlas.org/learn/cellines
Info; StRAP; -; https://strap.nci.nih.gov/celline_detail.php?sample_id=67
Publications


Stephen J. Gould, David Lee Valle;
An isoform of pex5p, the human PTS1 receptor, is required for the import of PTS2 proteins into peroxisomes.
Hum. Mol. Genet. 7:1195-1205(1998)


Elzbieta Kulig, Xiang Qian, Bernd W. Scheithauer, Norman L. Eberhardt, Ricardo V. Lloyd;
A human pituitary adenoma cell line proliferates and maintains some differentiated functions following expression of SV40 large T-antigen.
Endocr. Pathol. 9:169-184(1998)


Stephan Beck;
Complete MHC haplotype sequencing for common disease gene mapping.
Genome Res. 14:1176-1187(2004)

Cross-references
Cell line collections (Providers) AddexBio; P0012005/4972
ATCC; CRL-2522
CLS; 305222
Ubigene; YC-C080
Cell line databases/resources CLO; CLO_0001980
Cell_Model_Passport; SIDM01891
Lonza; 723
SKIP; SKIP001154
TOKU-E; 672
Biological sample resources ENCODE; ENCBS070WLP
ENCODE; ENCBS074ENC
ENCODE; ENCBS137RRI
ENCODE; ENCBS170GUW
ENCODE; ENCBS198NMJ
ENCODE; ENCBS335XLL
ENCODE; ENCBS339MSO
ENCODE; ENCBS488ZLU
ENCODE; ENCBS610AAA
ENCODE; ENCBS611AAA
ENCODE; ENCBS612AAA
ENCODE; ENCBS613AAA
ENCODE; ENCBS614AAA
ENCODE; ENCBS615AAA
ENCODE; ENCBS616AAA
ENCODE; ENCBS628EGC
ENCODE; ENCBS683XYV
ENCODE; ENCBS693PNC
ENCODE; ENCBS753AAA
ENCODE; ENCBS754AAA
ENCODE; ENCBS772THG
ENCODE; ENCBS815JWZ
ENCODE; ENCBS911DVL
ENCODE; ENCBS935PZD
CRISP screens repositories BioGRID_ORCS_Cell_line; 1125
Chemistry resources ChEMBL-Cells; CHEMBL3307781
ChEMBL-Targets; CHEMBL614358
PubChem_Cell_line; CVCL_3653
Encyclopedic resources Wikidata; Q54796903
Experimental variables resources EFO; EFO_0002779
Gene expression databases GEO; GSM248213
GEO; GSM248214
GEO; GSM472898
GEO; GSM472924
GEO; GSM472925
GEO; GSM579886
GEO; GSM579887
GEO; GSM736518
GEO; GSM736596
GEO; GSM749677
GEO; GSM749752
GEO; GSM749770
GEO; GSM923444
GEO; GSM945178
GEO; GSM945204
GEO; GSM945207
GEO; GSM945235
GEO; GSM2988896
GEO; GSM7701416
GEO; GSM7701417
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number35