Cellosaurus logo
expasy logo

Cellosaurus Hepa-1a 1/c/1 (CVCL_E4AR)

[Text version]
Cell line name Hepa-1a 1/c/1
Synonyms 1/c/1
Accession CVCL_E4AR
Resource Identification Initiative To cite this cell line use: Hepa-1a 1/c/1 (RRID:CVCL_E4AR)
Comments Characteristics: Show significantly reduced levels of albumin production (PubMed=6181572).
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: ChEBI; CHEBI_21759; N-methyl-N'-nitro-N-nitrosoguanidine (MNNG).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57L/J.
Hierarchy Parent: CVCL_E4AL (Hepa-1a)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=6181572; DOI=10.1007/BF01538707
Darlington G.J., Papaconstantinou J., Sammons D.W., Brown P.C., Wong E.Y., Esterman A.L., Kang J.
Generation and chracterization of variants of mouse hepatoma cells with defects in hepato-specific gene expression. I. Albumin synthesis variants.
Somatic Cell Genet. 8:451-464(1982)

PubMed=3431441; DOI=10.1016/s0076-6879(87)51006-0
Darlington G.J.
Liver cell lines.
Methods Enzymol. 151:19-38(1987)

Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1