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Cellosaurus 1BR3-hTERT PBRM1 KO 5 (CVCL_E3VD)

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Cell line name 1BR3-hTERT PBRM1 KO 5
Synonyms 1BR PBRM1 KO5; 1BR3-hTERT knockout for PBRM1 clone 5
Accession CVCL_E3VD
Resource Identification Initiative To cite this cell line use: 1BR3-hTERT PBRM1 KO 5 (RRID:CVCL_E3VD)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:30064; PBRM1.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11730; TERT.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E3V7 (1BR3-hTERT)
Children:
CVCL_E3WF (1BR3-hTERT PBRM1 KO 5 + EV)CVCL_E3WE (1BR3-hTERT PBRM1 KO 5 + PBRM1)
Sex of cell Male
Age at sampling 23Y
Category Telomerase immortalized cell line
Publications

PubMed=35902118; DOI=10.1101/gad.349249.121; PMCID=PMC9480851
Feng H.-G., Lane K.A., Roumeliotis T.I., Jeggo P.A., Somaiah N., Choudhary J.S., Downs J.A.
PBAF loss leads to DNA damage-induced inflammatory signaling through defective G2/M checkpoint maintenance.
Genes Dev. 36:790-806(2022)

Cross-references
Cell line collections (Providers) CancerTools; 161850
Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1