Cellosaurus cell line RBL-IV HR+ (CVCL_E3P7)

Cellosaurus RBL-IV HR+ (CVCL_E3P7)

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Cell line name

RBL-IV HR+

Synonyms

RBL-HR+; AB-CBF1-MCT-1; MCT-1

Accession

CVCL_E3P7

Resource Identification Initiative

To cite this cell line use: RBL-IV HR+ (RRID:CVCL_E3P7)

Comments

Problematic cell line: Misidentified/contaminated. Originally thought to be a mouse cell line, but later found to be derivative of RBL-IV (PubMed=102698; PubMed=6166481).
Transformant: ChEBI; CHEBI_232042; Beta-chloro-N-isopropyl-2-naphthaleneethanamine hydrochloride (ICI 42464).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: Basophil; CL=CL_0000767.

Disease

Rat leukemia (NCIt: C60428)

Species of origin

Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Wistar; RS=RS_0000955.

Hierarchy

Parent: CVCL_E3P6 (RBL-IV)
Children:

CVCL_0591 (RBL-2H3)

Category

Cancer cell line

Publications

PubMed=72105; DOI=10.4049/jimmunol.119.5.1757
Joel David Taurog, Guillermo Roberto Mendoza, William A. Hook, Reuben P. Siraganian, Henry Metzger;
Noncytotoxic IgE-mediated release of histamine and serotonin from murine mastocytoma cells.
J. Immunol. 119:1757-1761(1977)

PubMed=102698; DOI=10.4049/jimmunol.121.6.2584
Reuben P. Siraganian, Henry Metzger;
Evidence that the 'mouse mastocytoma' cell line (MCT-1) is of rat origin.
J. Immunol. 121:2584-2585(1978)

PubMed=6166481; DOI=10.1002/eji.1830110410
Edward L. Barsumian, Chaviva Isersky, Marianne G. Petrino, Reuben P. Siraganian;
IgE-induced histamine release from rat basophilic leukemia cell lines: isolation of releasing and nonreleasing clones.
Eur. J. Immunol. 11:317-323(1981)

PubMed=19669619; DOI=10.1007/s00011-009-0074-y
Egle Passante, Neil Frankish;
The RBL-2H3 cell line: its provenance and suitability as a model for the mast cell.
Inflamm. Res. 58:737-745(2009)

Entry history

Entry creation

19-Dec-2024

Last entry update

10-Apr-2025

Version number

2