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Cellosaurus U2OSEBNALTD3 (CVCL_E3JH)

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Cell line name U2OSEBNALTD3
Accession CVCL_E3JH
Resource Identification Initiative To cite this cell line use: U2OSEBNALTD3 (RRID:CVCL_E3JH)
Comments Population: Caucasian.
Biotechnology: Used in an expression system called QMCF Technology which allows transient mammalian expression system for recombinant protein production with high yields of up to 1g/L (Icosagen).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03211; Epstein-Barr virus (strain B95-8) EBNA1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P0DOJ5; Murine polyomavirus (strain A3) (MPyV) large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 157703; Murine polyomavirus (strain A3) (MPyV).
Miscellaneous: Information on transfected genes from personal communication of Mannik, Andres.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=23357356; DOI=10.1016/j.bbamem.2013.01.011
Piret Arukuusk, Ly Porosk, Nikita Oskolkov, Dana-Maria Copolovici, Helerin Margus, Kart Padari, Kaidi Moll, Julia Maslovskaja, Radi Tegova, Gaily Kivi, Andres Tover ...Show all 14 authors... , Margus Pooga, Mart Ustav, Ulo Langel; Show fewer authors
New generation of efficient peptide-based vectors, NickFects, for the delivery of nucleic acids.
Biochim. Biophys. Acta 1828:1365-1373(2013)

Entry history
Entry creation19-Dec-2024
Last entry update14-Aug-2025
Version number2