ID   U2OSEBNALTD3
AC   CVCL_E3JH
RX   PubMed=23357356;
CC   Population: Caucasian.
CC   Biotechnology: Used in an expression system called QMCF Technology which allows transient mammalian expression system for recombinant protein production with high yields of up to 1g/L (Icosagen).
CC   Sequence variation: Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03211; Epstein-Barr virus (strain B95-8) EBNA1.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P0DOJ5; Murine polyomavirus (strain A3) (MPyV) large T antigen.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR).
CC   Transformant: NCBI_TaxID; 157703; Murine polyomavirus (strain A3) (MPyV).
CC   Miscellaneous: Information on transfected genes from personal communication of Mannik, Andres.
CC   Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
DI   NCIt; C9145; Osteosarcoma
DI   ORDO; Orphanet_668; Osteosarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0042 ! U2OS
SX   Female
AG   15Y
CA   Cancer cell line
DT   Created: 19-12-24; Last updated: 19-12-24; Version: 1
//
RX   PubMed=23357356; DOI=10.1016/j.bbamem.2013.01.011;
RA   Arukuusk P., Porosk L., Oskolkov N., Copolovici D.-M., Margus H.,
RA   Padari K., Moll K., Maslovskaja J., Tegova R., Kivi G., Tover A.,
RA   Pooga M., Ustav M., Langel U.;
RT   "New generation of efficient peptide-based vectors, NickFects, for the
RT   delivery of nucleic acids.";
RL   Biochim. Biophys. Acta 1828:1365-1373(2013).
//