Cellosaurus logo
expasy logo
Due to maintenance work, this service will be unavailable from Mon Nov 11 17:30 until Tue Nov 12 09:00 CET. Apologies for the inconvenience.

Cellosaurus HKGZ-CC (CVCL_E329)

[Text version]
Cell line name HKGZ-CC
Synonyms HKGZCC
Accession CVCL_E329
Resource Identification Initiative To cite this cell line use: HKGZ-CC (RRID:CVCL_E329)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Chinese.
Doubling time: ~48 hours (PubMed=17914572).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gln61His (c.183A>C); ClinVar=VCV000177881; Zygosity=Unspecified (DepMap=ACH-001852).
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 76Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001852

Markers:
AmelogeninX,Y
CSF1PO10
D3S135816
D5S8189,11
D7S8208,11
D8S117911,14
D13S31710,11
D16S5399,11
D18S5116
D21S1130
FGA22,24
Penta D13
Penta E15
TH017,10
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=17914572; DOI=10.3892/or.18.5.1195
Ma S., Hu L., Huang X.-H., Cao L.-Q., Chan K.-W., Wang Q., Guan X.-Y.
Establishment and characterization of a human cholangiocarcinoma cell line.
Oncol. Rep. 18:1195-1200(2007)

CLPUB00275
Zach S., Birgin E., Ruckert F.
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442; PMCID=PMC5458737
Saha S.K., Gordan J.D., Kleinstiver B.P., Vu P., Najem M.S., Yeo J.-C., Shi L., Kato Y., Levin R.S., Webber J.T., Damon L.J., Egan R.K., Greninger P., McDermott U., Garnett M.J., Jenkins R.L., Rieger-Christ K.M., Sullivan T.B., Hezel A.F., Liss A.S., Mizukami Y., Goyal L., Ferrone C.R., Zhu A.X.-X., Joung J.K., Shokat K.M., Benes C.H., El-Bardeesy N.
Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.
Cancer Discov. 6:727-739(2016)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155
Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y., Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S., Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cross-references
Cell line databases/resources cancercelllines; CVCL_E329
Cell_Model_Passport; SIDM01819
DepMap; ACH-001852
Encyclopedic resources Wikidata; Q54889772
Entry history
Entry creation22-Oct-2012
Last entry update02-May-2024
Version number17