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Cellosaurus HKGZ-CC (CVCL_E329)

[Text version]
Cell line name HKGZ-CC
Synonyms HKGZCC
Accession CVCL_E329
Resource Identification Initiative To cite this cell line use: HKGZ-CC (RRID:CVCL_E329)
Comments Part of: Biliary tract cancer cell line atlas.
Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Population: Chinese.
Doubling time: ~48 hours (PubMed=17914572).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61His (c.183A>C); ClinVar=VCV000177881; Zygosity=Unspecified (DepMap=ACH-001852).
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 76Y
Category Cancer cell line
STR profile Source(s): DepMap=ACH-001852

Markers:
AmelogeninX,Y
CSF1PO10
D3S135816
D5S8189,11
D7S8208,11
D8S117911,14
D13S31710,11
D16S5399,11
D18S5116
D21S1130
FGA22,24
Penta D13
Penta E15
TH017,10
TPOX8
vWA16,18

Run an STR similarity search on this cell line
Publications

PubMed=17914572; DOI=10.3892/or.18.5.1195
Stephanie Ma, Liang Hu, Xiao-Hui Huang, Liang-Qi Cao, Kwok-Wah Chan, Qian Wang, Xin-Yuan Guan;
Establishment and characterization of a human cholangiocarcinoma cell line.
Oncol. Rep. 18:1195-1200(2007)

CLPUB00275
Sebastian Zach, Emrullah Birgin, Felix Ruckert;
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=27231123; DOI=10.1158/2159-8290.CD-15-1442; PMCID=PMC5458737
Supriya Kumar Saha, John D. Gordan, Benjamin P. Kleinstiver, Phuong Vu, Mortada S. Najem, Jia-Chi Yeo, Lei Shi, Yasutaka Kato, Rebecca S. Levin, James T. Webber, Leah J. Damon ...Show all 28 authors... , Regina K. Egan, Patricia Greninger, Ultan McDermott, Mathew J. Garnett, Roger L. Jenkins, Kimberly M. Rieger-Christ, Travis B. Sullivan, Aram Francis Hezel, Andrew S. Liss, Yusuke Mizukami, Lipika Goyal, Cristina Rosa Ferrone, Andrew Xiu-Xuan Zhu, Jae Keith Joung, Kevan Michael Shokat, Cyril Henri Benes, Nabeel M. Bardeesy; Show fewer authors
Isocitrate dehydrogenase mutations confer dasatinib hypersensitivity and SRC dependence in intrahepatic cholangiocarcinoma.
Cancer Discov. 6:727-739(2016)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155
Abdulkadir Isidan, Ali Yenigun, Daiki Soma, Eric Aksu, Kevin Lopez, Yujin Park, Arthur Cross-Najafi, Ping Li, Debjyoti Kundu, Michael G. House, Sanjukta Chakraborty ...Show all 17 authors... , Shannon Glaser, Lindsey Kennedy, Heather Francis, Wen-Jun Zhang, Gianfranco D. Alpini, Burcin Ekser; Show fewer authors
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

PubMed=39026794; DOI=10.1101/2024.07.04.601970; PMCID=PMC11257448
Vindhya Vijay, Negin Karisani, Lei Shi, Yu-Han Hung, Phuong Vu, Prabhat Kattel, Lauren Kenney, Joshua Merritt, Ramzi Adil, Qi-Biao Wu, Yuan-Li Zhen ...Show all 39 authors... , Robert Morris, Johannes Kreuzer, Meena Kathiresan, Xcanda Ixchel Herrera Lopez, Haley Ellis, Ilaria G. Gritti, Lilian Lecorgne, Ines Farag, Alexandra Popa, William Shen, Hiroyuki Kato, Qin Xu, Eranga Roshan Balasooriya, Meng-Ju Wu, Saireudee Chaturantabut, Robin Kate Kelley, James Mark Cleary, Michael Scott Lawrence, David E. Root, Cyril Henri Benes, Vikram Deshpande, Dejan Juric, William Raj Sellers, Cristina Rosa Ferrone, Wilhelm Haas, Francisca Vazquez, Gad Getz, Nabeel M. Bardeesy; Show fewer authors
Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targets.
bioRxiv 2024:07.04.601970-07.04.601970(2024)

Cross-references
Cell line databases/resources cancercelllines; CVCL_E329
Cell_Model_Passport; SIDM01819
DepMap; ACH-001852
Encyclopedic resources Wikidata; Q54889772
Entry history
Entry creation22-Oct-2012
Last entry update19-Dec-2024
Version number18