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Cellosaurus YES-2 (CVCL_E322)

[Text version]
Cell line name YES-2
Synonyms YES 2; YES2
Accession CVCL_E322
Resource Identification Initiative To cite this cell line use: YES-2 (RRID:CVCL_E322)
Comments Population: Japanese.
Doubling time: 22.9 hours (PubMed=1770930); 67.2 hours (DOI=10.5833/jjgs.27.1885); 23.7 hours (Note=At 102th passage) (CelloPub=CLPUB00005).
Omics: Transcriptomics; Microarray.
Omics: Variations; Array-based CGH.
Derived from site: In situ; Esophagus; UBERON=UBERON_0001043.
HLA typing Source: PubMed=18575732
Class I
HLA-AA*24
HLA-BB*01,40
HLA-CC*03,07
Disease Esophageal squamous cell carcinoma (NCIt: C4024)
Squamous cell carcinoma of the esophagus (ORDO: Orphanet_99977)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_S526 (YES-2CSC)
Sex of cell Male
Age at sampling 81Y
Category Cancer cell line
Publications

PubMed=1770930
Takuo Murakami, Masayuki Nakamura, Hiroshi Kusanagi, Takashi Suzuki;
Establishment and characterization of human esophageal carcinoma cell lines -- especially the role of the serum-free culture.
Nihon Geka Gakkai Zasshi 92:1563-1570(1991)

CLPUB00005
Masayuki Nakamura, Takuo Murakami, Koichiro Sakata, Hiroshi Kusanagi, Toshihiro Saeki, Hiroyuki Uchisako, Hiroto Hayashi, Akira Tangoku, Takashi Suzuki;
Establishment and characterization of a new human esophageal cancer cell line (YES-2).
Bull. Yamaguchi Med. Sch. 41:149-153(1994)

DOI=10.5833/jjgs.27.1885
Hiroshi Kusanagi;
Effect of epidermal growth factor (EGF) on human esophageal cancer cell lines in a protein-free medium and the expression of EGF receptors on the cells.
Nihon Shokaki Geka Gakkai Zasshi 27:1885-1891(1994)

PubMed=8590302; DOI=10.1089/jir.1995.15.1005
Masaaki Oka, Kunitaka Hirose, Norio Iizuka, Keiko Aoyagi, Kohtaro Yamamoto, Toshihiro Abe, Shoichi Hazama, Takashi Suzuki;
Cytokine mRNA expression patterns in human esophageal cancer cell lines.
J. Interferon Cytokine Res. 15:1005-1009(1995)

PubMed=8974001; DOI=10.1089/jir.1996.16.1001
Masaaki Oka, Norio Iizuka, Kohtaro Yamamoto, Toshikazu Gondo, Toshihiro Abe, Shoichi Hazama, Yumiko Akitomi, Yoshio Koishihara, Yoshiyuki Ohsugi, Yuzou Ooba, Tokuhiro Ishihara, Takashi Suzuki;
The influence of interleukin-6 on the growth of human esophageal cancer cell lines.
J. Interferon Cytokine Res. 16:1001-1006(1996)

PubMed=11115554; DOI=10.3892/ijo.18.1.157
Teruhiko Fujii, Seiya Kato, Hideaki Yamana, Yuichi Tanaka, Hiromasa Fujita, Kazuo Shirouzu, Minoru Morimatsu;
Expression of G1 cell cycle markers and the effect of adenovirus-mediated overexpression of p21Waf-1 in squamous cell carcinoma of the esophagus.
Int. J. Oncol. 18:157-163(2001)

PubMed=18575732; DOI=10.3892/or.20.1.155
Toru Kawaoka, Masaaki Oka, Motonari Takashima, Tomio Ueno, Koutaro Yamamoto, Noboru Yahara, Shigefumi Yoshino, Shoichi Hazama;
Adoptive immunotherapy for pancreatic cancer: cytotoxic T lymphocytes stimulated by the MUC1-expressing human pancreatic cancer cell line YPK-1.
Oncol. Rep. 20:155-163(2008)

PubMed=18973137; DOI=10.1002/gcc.20626
Takashi Sugimoto, Naohiko Seki, Satoya Shimizu, Naoko Kikkawa, Jun Tsukada, Hideaki Shimada, Keita Sasaki, Toyoyuki Hanazawa, Yoshitaka Okamoto, Akira Hata;
The galanin signaling cascade is a candidate pathway regulating oncogenesis in human squamous cell carcinoma.
Genes Chromosomes Cancer 48:132-142(2009)

PubMed=20515944; DOI=10.1158/1535-7163.MCT-09-0918; PMCID=PMC2884061
Naoko Seki, Uhi Toh, Thomas J. Sayers, Teruhiko Fujii, Motoshi Miyagi, Yoshito Akagi, Jingo Kusukawa, Masayoshi Kage, Kazuo Shirouzu, Hideaki Yamana;
Bortezomib sensitizes human esophageal squamous cell carcinoma cells to TRAIL-mediated apoptosis via activation of both extrinsic and intrinsic apoptosis pathways.
Mol. Cancer Ther. 9:1842-1851(2010)

PubMed=21191746; DOI=10.1007/s11684-010-0260-x
Jun-Fang Ji, Kun Wu, Min Wu, Qi-Min Zhan;
p53 functional activation is independent of its genotype in five esophageal squamous cell carcinoma cell lines.
Front. Med. China 4:412-418(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_E322
Encyclopedic resources Wikidata; Q54995400
Gene expression databases GEO; GSM301575
Polymorphism and mutation databases Cosmic; 2395009
Progenetix; CVCL_E322
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number17