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Cellosaurus MHCF5 (CVCL_E2YC)

[Text version]
Cell line name MHCF5
Accession CVCL_E2YC
Resource Identification Initiative To cite this cell line use: MHCF5 (RRID:CVCL_E2YC)
Comments Characteristics: Established after repeatedly transplanting the parent cell line into NOD-SCID mice. The developed tumors were dissociated and passaged on culture dishes several times (PubMed=34158541).
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P26662; Hepatitis C virus genotype 1b genome polyprotein.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Hepatocellular carcinoma of the mouse (NCIt: C38756)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: HCV-Tg.
Hierarchy Parent: CVCL_E2YB (MHCF1)
Category Cancer cell line
Publications

PubMed=34158541; DOI=10.1038/s41598-021-92128-9; PMCID=PMC8219799
Shirasaki T., Murai K., Honda M., Okada H., Innami Y., Yamada A., Shimakami T., Kawaguchi K., Yamashita T., Sakai Y., Kaneko S.
Establishment of liver tumor cell lines from atherogenic and high fat diet fed hepatitis C virus transgenic mice.
Sci. Rep. 11:13021.1-13021.14(2021)

Entry history
Entry creation10-Sep-2024
Last entry update10-Apr-2025
Version number2