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Cellosaurus K3OHD (CVCL_E2WG)

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Cell line name K3OHD
Synonyms K 3 OHD; K3 OHD
Accession CVCL_E2WG
Resource Identification Initiative To cite this cell line use: K3OHD (RRID:CVCL_E2WG)
Comments Group: Plant cell line.
Characteristics: Used to transform digitoxin into deacetyllanatoside C, a precursor of digoxin (DOI=10.1007/BF02933754).
Derived from site: In situ; Vascular leaf; PO=PO_0009025.
Species of origin Digitalis lanata (Grecian foxglove) (NCBI Taxonomy: 49450)
Breed/subspecies: Cultivar EHRH.
Category Spontaneously immortalized cell line
Publications

PubMed=17265224; DOI=10.1055/s-2006-962373
Wolfgang Kreis, Ernst Reinhard;
12beta-hydroxylation of digitoxin by suspension-cultured Digitalis lanata cells. Production of deacetyllanatoside C using a two-stage Culture method.
Planta Med. 54:143-148(1988)

DOI=10.1007/BF02933754
Jeong-Woo Choi, Young-Kee Kim, Hyun-Kyu Park, Won Hong Lee, Dong-Il Kim;
Kinetic model for biotransformation of digitoxin in plant cell suspension culture of Digitalis lanata.
Biotechnol. Bioprocess Eng. 4:281-286(1999)

PubMed=20514608; DOI=10.1055/s-0030-1250007
Mona Ernst, Rodrigo Maia de Padua, Vanessa Herl, Frieder Muller-Uri, Wolfgang Kreis;
Expression of 3beta-HSD and P5betaR, genes respectively coding for Delta5-3beta-hydroxysteroid dehydrogenase and progesterone 5beta-reductase, in leaves and cell cultures of Digitalis lanata EHRH.
Planta Med. 76:923-927(2010)

Cross-references
Anatomy/cell type resources BTO; BTO_0005622
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2