ID   K3OHD
AC   CVCL_E2WG
SY   K 3 OHD; K3 OHD
DR   BTO; BTO_0005622
RX   DOI=10.1007/BF02933754;
RX   PubMed=17265224;
RX   PubMed=20514608;
CC   Group: Plant cell line.
CC   Characteristics: Used to transform digitoxin into deacetyllanatoside C, a precursor of digoxin (DOI=10.1007/BF02933754).
CC   Derived from site: In situ; Vascular leaf; PO=PO_0009025.
CC   Breed/subspecies: Cultivar EHRH.
OX   NCBI_TaxID=49450; ! Digitalis lanata (Grecian foxglove)
CA   Spontaneously immortalized cell line
DT   Created: 10-09-24; Last updated: 19-12-24; Version: 2
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RX   PubMed=17265224; DOI=10.1055/s-2006-962373;
RA   Kreis, Wolfgang
RA   Reinhard, Ernst
RT   "12beta-hydroxylation of digitoxin by suspension-cultured Digitalis
RT   lanata cells. Production of deacetyllanatoside C using a two-stage
RT   Culture method.";
RL   Planta Med. 54:143-148(1988).
//
RX   DOI=10.1007/BF02933754;
RA   Choi, Jeong-Woo
RA   Kim, Young-Kee
RA   Park, Hyun-Kyu
RA   Lee, Won Hong
RA   Kim, Dong-Il
RT   "Kinetic model for biotransformation of digitoxin in plant cell
RT   suspension culture of Digitalis lanata.";
RL   Biotechnol. Bioprocess Eng. 4:281-286(1999).
//
RX   PubMed=20514608; DOI=10.1055/s-0030-1250007;
RA   Ernst, Mona
RA   de Padua, Rodrigo Maia
RA   Herl, Vanessa
RA   Muller-Uri, Frieder
RA   Kreis, Wolfgang
RT   "Expression of 3beta-HSD and P5betaR, genes respectively coding for
RT   Delta5-3beta-hydroxysteroid dehydrogenase and progesterone
RT   5beta-reductase, in leaves and cell cultures of Digitalis lanata
RT   EHRH.";
RL   Planta Med. 76:923-927(2010).
//