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Cellosaurus NAB-2 (CVCL_E219)

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Cell line name NAB-2
Synonyms NAB2; Nab2; North American Burkitt-2
Accession CVCL_E219
Resource Identification Initiative To cite this cell line use: NAB-2 (RRID:CVCL_E219)
Comments Population: Caucasian.
Virology: The single copy EBV genome is integrated on chromosome 2p13 between REL and BCL11A.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Variations; Array-based CGH.
Derived from site: In situ; Retroperitoneal space; UBERON=UBERON_0003693.
Cell type: B-cell; CL=CL_0000236.
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9T72 (NAB)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=1697668
Nicholas Constantin Popescu, James Eric Dahlberg, Dharam Vir Ablashi, M. Monastier, Constantin A. Bona, Joseph A. DiPaolo, W. Craig Hooper, David C. Swan;
Oncogene expression and immunoglobulin synthesis in a North American Burkitt (NAB-2) lymphoma cell line with a 8;22 chromosome translocation.
Oncogene Res. 5:295-303(1990)

PubMed=15241441; DOI=10.1038/labinvest.3700152
Wen-Juan Luo, Tetsuya Takakuwa, Maria Francisca Ham, Naoki Wada, Angen Liu, Shigeki Fujita, Emiko Sakane-Ishikawa, Katsuyuki Aozasa;
Epstein-Barr virus is integrated between REL and BCL-11A in American Burkitt lymphoma cell line (NAB-2).
Lab. Invest. 84:1193-1199(2004)

PubMed=16960149; DOI=10.1182/blood-2006-06-026500
Cinta Mestre-Escorihuela, Fanny Rubio-Moscardo, Jose A. Richter, Reiner Siebert, Joan Climent, Vicente Fresquet, Elena Beltran, Xabier Agirre, Isabel Marugan, Miguel Marin, Andreas Rosenwald ...Show all 21 authors... , Kei-ji Sugimoto, Luise M. Wheat, E. Loraine Karran, Juan Fernando Garcia Garcia, Lydia Sanchez-Verde, Felipe Prosper, Louis Michael Staudt, Daniel Pinkel, Martin John Swinnerton Dyer, Jose Angel Martinez-Climent; Show fewer authors
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas.
Blood 109:271-280(2007)

Cross-references
Cell line databases/resources cancercelllines; CVCL_E219
Encyclopedic resources Wikidata; Q54907363
Gene expression databases GEO; GSM115811
Polymorphism and mutation databases Cosmic; 2297023
Progenetix; CVCL_E219
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number19