Cellosaurus cell line NAB-2 (CVCL

Cellosaurus NAB-2 (CVCL_E219)

Cross-references
Cell line name	NAB-2
Synonyms	NAB2; Nab2; North American Burkitt-2
Accession	CVCL_E219
Resource Identification Initiative	To cite this cell line use: NAB-2 (RRID:CVCL_E219)
Comments	Population: Caucasian. Virology: The single copy EBV genome is integrated on chromosome 2p13 between REL and BCL11A. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Omics: Variations; Array-based CGH. Derived from site: In situ; Retroperitoneal space; UBERON=UBERON_0003693. Cell type: B-cell; CL=CL_0000236.
Disease	EBV-related Burkitt lymphoma (NCIt: C27694) Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_9T72 (NAB)
Sex of cell	Female
Age at sampling	15Y
Category	Cancer cell line
Publications	PubMed=1697668 Popescu N.C., Dahlberg J.E., Ablashi D.V., Monastier M., Bona C.A., DiPaolo J.A., Hooper W.C., Swan D.C. Oncogene expression and immunoglobulin synthesis in a North American Burkitt (NAB-2) lymphoma cell line with a 8;22 chromosome translocation. Oncogene Res. 5:295-303(1990) PubMed=15241441; DOI=10.1038/labinvest.3700152 Luo W.-J., Takakuwa T., Ham M.F., Wada N., Liu A., Fujita S., Sakane-Ishikawa E., Aozasa K. Epstein-Barr virus is integrated between REL and BCL-11A in American Burkitt lymphoma cell line (NAB-2). Lab. Invest. 84:1193-1199(2004) PubMed=16960149; DOI=10.1182/blood-2006-06-026500 Mestre-Escorihuela C., Rubio-Moscardo F., Richter J.A., Siebert R., Climent J., Fresquet V., Beltran E., Agirre X., Marugan I., Marin M., Rosenwald A., Sugimoto K.-j., Wheat L.M., Karran E.L., Garcia J.F., Sanchez-Verde L., Prosper F., Staudt L.M., Pinkel D., Dyer M.J.S., Martinez-Climent J.A. Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas. Blood 109:271-280(2007)
Cell line databases/resources	cancercelllines; CVCL_E219
Encyclopedic resources	Wikidata; Q54907363
Gene expression databases	GEO; GSM115811
Polymorphism and mutation databases	Cosmic; 2297023 Progenetix; CVCL_E219
Entry history
Entry creation	22-Oct-2012
Last entry update	10-Apr-2025
Version number	19