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Cellosaurus HyCyte DU145 KO-hLncRNA (CVCL_E1JR)

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Cell line name HyCyte DU145 KO-hLncRNA
Synonyms hLncRNA knockout DU145
Accession CVCL_E1JR
Resource Identification Initiative To cite this cell line use: HyCyte DU145 KO-hLncRNA (RRID:CVCL_E1JR)
Comments Population: Caucasian.
Characteristics: This cell line is a knock-out for a transcript (Ensembl ENST00000510619) from a non-coding RNA gene (Ensembl ENSG00000251194) not yet in HGNC.
Doubling time: 48-72 hours (Hysigen=CGKO-M2632).
Derived from site: Metastatic; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Asp84Tyr (c.250G>T) (p.Arg98Leu, c.293G>T); ClinVar=VCV000376306; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; p.Lys715Ter (c.2143A>T); ClinVar=VCV001786615; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Lys178fs*86 (c.532_536delAAGCC); Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro223Leu (c.668C>T); ClinVar=VCV000234214; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val274Phe (c.820G>T); ClinVar=VCV000376674; Zygosity=Heterozygous (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0105 (DU145)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Hysigen; CGKO-M2632
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2