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Cellosaurus Ubigene PANC-1 PTEN KO (CVCL_E1AK)

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Cell line name Ubigene PANC-1 PTEN KO
Synonyms PTEN Knockout cell line (PANC-1)
Accession CVCL_E1AK
Resource Identification Initiative To cite this cell line use: Ubigene PANC-1 PTEN KO (RRID:CVCL_E1AK)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:9588; PTEN.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0480 (PANC-1)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Ubigene; YKO-HJ117
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2