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Cellosaurus OV-MZ-22 (CVCL_E117)

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Cell line name OV-MZ-22
Synonyms OVarian-MainZ-22
Accession CVCL_E117
Resource Identification Initiative To cite this cell line use: OV-MZ-22 (RRID:CVCL_E117)
Comments Doubling time: 42 hours (PubMed=11733966).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Sequence variations
Disease Ovarian carcinosarcoma (NCIt: C9192)
Malignant mixed Mullerian tumor of the ovary (ORDO: Orphanet_213512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=11242531; DOI=10.1089/10430340150504019
Ansgar Bruning, Tanja Kohler, Sven Roy Quist, Shan Wang-Gohrke, Volker Jochen Mobus, Rolf Kreienberg, Ingo Bernard Runnebaum;
Adenoviral transduction efficiency of ovarian cancer cells can be limited by loss of integrin beta3 subunit expression and increased by reconstitution of integrin alphaVbeta3.
Hum. Gene Ther. 12:391-399(2001)

PubMed=11733966; DOI=10.1006/gyno.2001.6425
Volker Jochen Mobus, Claus-Dieter Gerharz, Wolfgang Weikel, Oliver Merk, Liane Dreher, Rolf Kreienberg, Roland Moll;
Characterization of a human carcinosarcoma cell line of the ovary established after in vivo change of histologic differentiation.
Gynecol. Oncol. 83:523-532(2001)

PubMed=11925137; DOI=10.1006/gyno.2002.6597
Matthias Oppitz, Volker Jochen Mobus, S. Brock, Ulrich Drews;
Muscarinic receptors in cell lines from ovarian carcinoma: negative correlation with survival of patients.
Gynecol. Oncol. 85:159-164(2002)

PubMed=15153938; DOI=10.1038/sj.cgt.7700727
Sven Roy Quist, Shan Wang-Gohrke, Tanja Kohler, Rolf Kreienberg, Ingo Bernard Runnebaum;
Cooperative effect of adenoviral p53 gene therapy and standard chemotherapy in ovarian cancer cells independent of the endogenous p53 status.
Cancer Gene Ther. 11:547-554(2004)

Cross-references
Cell line collections (Providers) ABM; T8234
Encyclopedic resources Wikidata; Q54936847
Entry history
Entry creation22-Oct-2012
Last entry update27-Nov-2025
Version number15