ID   OV-MZ-22
AC   CVCL_E117
DR   ABM; T8234
DR   Wikidata; Q54936847
RX   PubMed=11242531;
RX   PubMed=11733966;
RX   PubMed=15153938;
CC   Doubling time: 42 hours (PubMed=11733966).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=15153938).
DI   NCIt; C9192; Ovarian carcinosarcoma
DI   ORDO; Orphanet_213512; Malignant mixed Mullerian tumor of the ovary
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   56Y
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 10-04-25; Version: 14
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RX   PubMed=11242531; DOI=10.1089/10430340150504019;
RA   Bruning A., Kohler T., Quist S.R., Wang-Gohrke S., Mobus V.J.,
RA   Kreienberg R., Runnebaum I.B.;
RT   "Adenoviral transduction efficiency of ovarian cancer cells can be
RT   limited by loss of integrin beta3 subunit expression and increased by
RT   reconstitution of integrin alphaVbeta3.";
RL   Hum. Gene Ther. 12:391-399(2001).
//
RX   PubMed=11733966; DOI=10.1006/gyno.2001.6425;
RA   Mobus V.J., Gerharz C.-D., Weikel W., Merk O., Dreher L.,
RA   Kreienberg R., Moll R.;
RT   "Characterization of a human carcinosarcoma cell line of the ovary
RT   established after in vivo change of histologic differentiation.";
RL   Gynecol. Oncol. 83:523-532(2001).
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RX   PubMed=15153938; DOI=10.1038/sj.cgt.7700727;
RA   Quist S.R., Wang-Gohrke S., Kohler T., Kreienberg R., Runnebaum I.B.;
RT   "Cooperative effect of adenoviral p53 gene therapy and standard
RT   chemotherapy in ovarian cancer cells independent of the endogenous p53
RT   status.";
RL   Cancer Gene Ther. 11:547-554(2004).
//