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Cellosaurus Ubigene LS174T HMGB1 KO (CVCL_E0XI)

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Cell line name Ubigene LS174T HMGB1 KO
Synonyms HMGB1 Knockout cell line (LS 174T)
Accession CVCL_E0XI
Resource Identification Initiative To cite this cell line use: Ubigene LS174T HMGB1 KO (RRID:CVCL_E0XI)
Comments Population: Caucasian.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:4983; HMGB1.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Cell type: Epithelial cell of colon; CL=CL_0011108.
Sequence variations
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Ser45Phe (c.134C>T); ClinVar=VCV000017588; Zygosity=Unspecified (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Unspecified (from parent cell line).
Disease Colon adenocarcinoma (NCIt: C4349)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1384 (LS174T)
Sex of cell Female
Age at sampling 58Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Ubigene; YKO-H913
Entry history
Entry creation10-Sep-2024
Last entry update19-Dec-2024
Version number2