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Cellosaurus WA26 (CVCL_E081)

[Text version]
Cell line name WA26
Synonyms WAe026-A
Accession CVCL_E081
Resource Identification Initiative To cite this cell line use: WA26 (RRID:CVCL_E081)
Comments Group: Clinical grade pluripotent cell line.
From: University of Wisconsin; Madison; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-12-0197.
Omics: Genomics; Whole exome sequencing.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Ser (c.733G>A); ClinVar=VCV000012365; Zygosity=Unspecified; Note=Somatic mutation acquired during proliferation (PubMed=28445466).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): WiCell=wa26

Markers:
AmelogeninX
CSF1PO11
D5S81812
D7S82010
D13S31711,12
D16S53912,14
TH017,10
TPOX8,11
vWA17

Run an STR similarity search on this cell line
Web pages Info; WiCell; -; https://www.wicell.org/media/Ads/2013.ISSCR.DerivationFinal.pdf
Publications

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Florian T. Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier ...Show all 17 authors... , Robert E. Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A. McCarroll, Kevin Carl Eggan; Show fewer authors
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

Cross-references
Cell line collections (Providers) WiCell; wa26
Cell line databases/resources hPSCreg; WAe026-A
NIHhESC; NIHhESC-12-0197
Encyclopedic resources Wikidata; Q54993533
Entry history
Entry creation22-Oct-2012
Last entry update10-Apr-2025
Version number24