Cellosaurus COS/Fucci (CVCL_E071)
| Cell line name | COS/Fucci |
|---|---|
| Synonyms | COS-Fucci |
| Accession | CVCL_E071 |
| Resource Identification Initiative | To cite this cell line use: COS/Fucci (RRID:CVCL_E071) |
| Comments | Group: Non-human primate cell line. Characteristics: Used for study of cell cycle progression thanks to the inclusion of a Fucci (Fluorescent Ubiquitination-based Cell Cycle Indicator) construct. Characteristics: Transfected with the Fucci probe which consist of the fusion of monomeric Kusabira-Orange2 (mKO2) to the ubiquitination domain of human CDT1 (AA 30-120) and monomeric AzamiGreen (mAG) to the ubiquitination domain of human geminin (AA 1-110). Genetic integration: Method=Transfection/transduction; Gene=FPbase; HC91W; AzamiGreen (Note=Green fluorescent protein from G.fascicularis). Genetic integration: Method=Transfection/transduction; Gene=FPbase; 134NN; mKusabira-Orange2 (Note=mKO2, orange fluorescent protein derived from F.concinna Kusabira-Orange (KO)). Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:24576; CDT1 (Note=With p.Met1_Thr29del and p.Ser121_Leu546del). Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:17493; GMNN (Note=With p.Tyr111_Ile209del). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV6-1). Derived from site: In situ; Kidney; UBERON=UBERON_0002113. |
| Species of origin | Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) (NCBI Taxonomy: 9534) |
| Hierarchy | Parent: CVCL_0224 (COS-7) |
| Sex of cell | Male |
| Age at sampling | Adult |
| Category | Transformed cell line |
| Publications | PubMed=18267078; DOI=10.1016/j.cell.2007.12.033 |
| Cross-references | |
| Cell line collections (Providers) | RCB; RCB2814 |
| Cell line databases/resources | CLO; CLO_0050516 |
| Encyclopedic resources | Wikidata; Q54814317 |
| Entry history | |
| Entry creation | 22-Oct-2012 |
| Last entry update | 10-Apr-2025 |
| Version number | 17 |