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Cellosaurus COS-7 (CVCL_0224)

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Cell line name COS-7
Synonyms Cos-7; COS 7; Cos 7; COS7; Cos7; CV-1 in Origin Simian-7
Accession CVCL_0224
Resource Identification Initiative To cite this cell line use: COS-7 (RRID:CVCL_0224)
Comments Group: Non-human primate cell line.
Virology: Highly susceptible to infection by Zika virus (ZIKV) (PubMed=29468137).
Doubling time: ~35-48 hours (DSMZ=ACC-60); ~2 days (Note=Lot 03052018) (JCRB=IFO50068); ~34 hours (Note=Lot 02292000), ~30 hours (Note=Lots 11222004 and 10052007) (JCRB=JCRB9127).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV6-1).
Misspelling: COS-2; Note=Thanks to a personal communication of Galan, Jorge E. we we made aware that COS-2 was mistakenly used instead of COS-7 in 3 papers: PubMed=14662750, PubMed=17074883 and PubMed=19379694.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) (NCBI Taxonomy: 9534)
Hierarchy Parent: CVCL_0229 (CV-1)
Children:
CVCL_A5PZ (COS-7 1C7)CVCL_LH58 (COS-7 1E7)CVCL_Z935 (COS-7-InVitrus)
CVCL_0J76 (COS-7L)CVCL_E071 (COS/Fucci)CVCL_B7HB (COS7-moRIII)
CVCL_B7HC (COS7 moRIII-gamma)CVCL_B7HD (COS7-pc)CVCL_YJ78 (LINTERNA COS-7)
CVCL_D2UH (PDIS-4)
Sex of cell Male
Age at sampling Adult
Category Transformed cell line
Web pages https://en.wikipedia.org/wiki/COS_cells
http://www.cos-7.com/
https://micro.magnet.fsu.edu/primer/techniques/fluorescence/gallery/cells/cos7/cos7cells.html
https://www.olympus-lifescience.com/de/microscope-resource/primer/techniques/fluorescence/gallery/cells/agmindex/
https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/c/cell-lines-detail-5.html
https://www.quora.com/How-is-the-COS-7-cell-line-produced-and-what-is-its-application
Publications

PubMed=6260373; DOI=10.1016/0092-8674(81)90282-8
Gluzman Y.
SV40-transformed simian cells support the replication of early SV40 mutants.
Cell 23:175-182(1981)

PubMed=22059503; DOI=10.1186/1472-6750-11-102; PMCID=PMC3221628
Almeida J.L., Hill C.R., Cole K.D.
Authentication of African green monkey cell lines using human short tandem repeat markers.
BMC Biotechnol. 11:102.1-102.10(2011)

PubMed=29468137; DOI=10.5501/wjv.v7.i1.10; PMCID=PMC5807893
Himmelsbach K., Hildt E.
Identification of various cell culture models for the study of Zika virus.
World J. Virol. 7:10-20(2018)

Cross-references
Cell line collections (Providers) AddexBio; T0014002/35
ATCC; CRL-1651
BCRC; 60094
BCRJ; 0071
CCTCC; GDC0609
CLS; 605470
DSMZ; ACC-60
ECACC; 87021302
IBRC; C10146
ICLC; ATL96005
IZSLER; BS CL 103
JCRB; IFO50068
JCRB; JCRB9127
KCB; KCB 93019YJ
KCLB; 21651
NCBI_Iran; C143
RCB; RCB0539
TKG; TKG 0514
Cell line databases/resources CLO; CLO_0002597
CLO; CLO_0050508
MCCL; MCC:0000112
CLDB; cl890
CLDB; cl891
CLDB; cl892
CLDB; cl893
CCRID; 1101MON-PUMC000033
CCRID; 3101MONGNO2
CCRID; 3101MONSCSP508
CCRID; 5301MON-KCB93019YJ
DSMZCellDive; ACC-60
FCS-free; 47-11-47-1-8-9
Lonza; 587
TOKU-E; 993
Anatomy/cell type resources BTO; BTO:0000298
Chemistry resources ChEMBL-Cells; CHEMBL3307648
ChEMBL-Targets; CHEMBL614564
PubChem_Cell_line; CVCL_0224
Encyclopedic resources Wikidata; Q27556092
Experimental variables resources EFO; EFO_0022725
Medical resources MeSH; D019556
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number32