Cellosaurus HeLa/Fucci (CVCL_E070)
| Cell line name | HeLa/Fucci |
|---|---|
| Synonyms | HeLa/Fucci #4; HeLa.S-Fucci |
| Accession | CVCL_E070 |
| Resource Identification Initiative | To cite this cell line use: HeLa/Fucci (RRID:CVCL_E070) |
| Comments | Population: African American. Characteristics: Used for study of cell cycle progression thanks to the inclusion of a Fucci (Fluorescent Ubiquitination-based Cell Cycle Indicator) construct. Characteristics: Transfected with the Fucci probe which consist of the fusion of monomeric Kusabira-Orange2 (mKO2) to the ubiquitination domain of human CDT1 (aa 30-120) and monomeric AzamiGreen (mAG) to the ubiquitination domain of human geminin (aa 1-110). Genetic integration: Method=Transfection/transduction; Gene=FPbase; HC91W; AzamiGreen (Note=Green fluorescent protein from G.fascicularis). Genetic integration: Method=Transfection/transduction; Gene=FPbase; 134NN; mKusabira-Orange2 (Note=mKO2, orange fluorescent protein derived from F.concinna Kusabira-Orange (KO)). Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:24576; CDT1 (Note=With p.Met1_Thr29del and p.Ser121_Leu546del). Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:17493; GMNN (Note=With p.Tyr111_Ile209del). Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002. |
| Disease | Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0030 (HeLa) |
| Sex of cell | Female |
| Age at sampling | 30Y6M |
| Category | Cancer cell line |
| Publications | PubMed=18267078; DOI=10.1016/j.cell.2007.12.033 |
| Cross-references | |
| Cell line collections (Providers) | RCB; RCB2812 |
| Cell line databases/resources | CLO; CLO_0050931 |
| Encyclopedic resources | Wikidata; Q54882691 |
| Entry history | |
| Entry creation | 22-Oct-2012 |
| Last entry update | 10-Apr-2025 |
| Version number | 17 |