Cellosaurus logo
expasy logo

Cellosaurus Jones (CVCL_DN28)

[Text version]
Cell line name Jones
Synonyms JONES
Accession CVCL_DN28
Resource Identification Initiative To cite this cell line use: Jones (RRID:CVCL_DN28)
Comments Part of: FACC canine tumor cell line panel.
Doubling time: 14 hours (PubMed=27257868).
Omics: Deep exome analysis.
Omics: Transcriptome analysis by microarray.
Sequence variations
  • Mutation; VGNC; 38196; ASXL1; Simple; p.Gly618fs (c.1850dupG); Zygosity=Heterozygous (PubMed=31175136).
  • Mutation; VGNC; 43959; NRAS; Simple; p.Gln61Arg (c.182A>G); Zygosity=Heterozygous (PubMed=27197945; PubMed=31175136).
  • Mutation; VGNC; 44567; PTEN; Simple; p.Asp246fs (c.734dupA); Zygosity=Heterozygous (PubMed=31175136).
Disease Canine melanoma (NCIt: C120298)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9615)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=27197945; PubMed=31175136

Dog FHC2010235,239
Dog FHC2054168,172
Dog FHC2079271,279
Dog PEZ1123
Dog PEZ12267,270
Dog PEZ20180
Dog PEZ3127,129
Dog PEZ5103,111
Dog PEZ6183,191
Dog PEZ8240

Run an STR similarity search on this cell line

PubMed=27257868; DOI=10.1371/journal.pone.0156689
Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.
Intrinsic radiosensitivity and cellular characterization of 27 canine cancer cell lines.
PLoS ONE 11:E0156689-E0156689(2016)

PubMed=26842912; DOI=10.1111/vco.12197
Hartley G., Faulhaber E., Caldwell A., Coy J., Kurihara J., Guth A., Regan D., Dow S.
Immune regulation of canine tumour and macrophage PD-L1 expression.
Vet. Comp. Oncol. 15:534-549(2017)

PubMed=27197945; DOI=10.1111/vco.12192
Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.
The Flint Animal Cancer Center (FACC) canine tumour cell line panel: a resource for veterinary drug discovery, comparative oncology and translational medicine.
Vet. Comp. Oncol. 15:481-492(2017)

PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346
Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.
Identifying candidate druggable targets in canine cancer cell lines using whole exome sequencing.
Mol. Cancer Ther. 18:1460-1471(2019)

Encyclopedic resources Wikidata; Q54899042
Gene expression databases GEO; GSM1974791
Entry history
Entry creation13-Jul-2016
Last entry update21-Mar-2023
Version number10