ID   Jones
AC   CVCL_DN28
SY   JONES
DR   GEO; GSM1974791
DR   Wikidata; Q54899042
RX   PubMed=26842912;
RX   PubMed=27197945;
RX   PubMed=27257868;
RX   PubMed=31175136;
CC   Part of: FACC canine tumor cell line panel.
CC   Doubling time: 14 hours (PubMed=27257868).
CC   Sequence variation: Mutation; VGNC; 38196; ASXL1; Simple; p.Gly618fs (c.1850dupG); Zygosity=Heterozygous (PubMed=31175136).
CC   Sequence variation: Mutation; VGNC; 43959; NRAS; Simple; p.Gln61Arg (c.182A>G); Zygosity=Heterozygous (PubMed=27197945; PubMed=31175136).
CC   Sequence variation: Mutation; VGNC; 44567; PTEN; Simple; p.Asp246fs (c.734dupA); Zygosity=Heterozygous (PubMed=31175136).
CC   Omics: Deep exome analysis.
CC   Omics: Transcriptome analysis by microarray.
ST   Source(s): PubMed=27197945; PubMed=31175136
ST   Dog FHC2010: 235,239
ST   Dog FHC2054: 168,172
ST   Dog FHC2079: 271,279
ST   Dog PEZ1: 123
ST   Dog PEZ3: 127,129
ST   Dog PEZ5: 103,111
ST   Dog PEZ6: 183,191
ST   Dog PEZ8: 240
ST   Dog PEZ12: 267,270
ST   Dog PEZ20: 180
DI   NCIt; C120298; Canine melanoma
OX   NCBI_TaxID=9615; ! Canis lupus familiaris (Dog)
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 13-07-16; Last updated: 21-03-23; Version: 10
//
RX   PubMed=26842912; DOI=10.1111/vco.12197;
RA   Hartley G., Faulhaber E., Caldwell A., Coy J., Kurihara J., Guth A.,
RA   Regan D.P., Dow S.W.;
RT   "Immune regulation of canine tumour and macrophage PD-L1 expression.";
RL   Vet. Comp. Oncol. 15:534-549(2017).
//
RX   PubMed=27197945; DOI=10.1111/vco.12192;
RA   Fowles J.S., Dailey D.D., Gustafson D.L., Thamm D.H., Duval D.L.;
RT   "The Flint Animal Cancer Center (FACC) canine tumour cell line panel:
RT   a resource for veterinary drug discovery, comparative oncology and
RT   translational medicine.";
RL   Vet. Comp. Oncol. 15:481-492(2017).
//
RX   PubMed=27257868; DOI=10.1371/journal.pone.0156689;
RA   Maeda J., Froning C.E., Brents C.A., Rose B.J., Thamm D.H., Kato T.A.;
RT   "Intrinsic radiosensitivity and cellular characterization of 27 canine
RT   cancer cell lines.";
RL   PLoS ONE 11:E0156689-E0156689(2016).
//
RX   PubMed=31175136; DOI=10.1158/1535-7163.MCT-18-1346;
RA   Das S., Idate R., Cronise K.E., Gustafson D.L., Duval D.L.;
RT   "Identifying candidate druggable targets in canine cancer cell lines
RT   using whole exome sequencing.";
RL   Mol. Cancer Ther. 18:1460-1471(2019).
//