| Publications | PubMed=25758528; DOI=10.1038/ncomms7377; PMCID=PMC4357281
Matthew J. Niederst, Lecia VanDam Sequist, John T. Poirier, Craig H. Mermel, Elizabeth L. Lockerman, Angel R. Garcia, Ryohei Katayama, Carlotta Costa, Kenneth N. Ross, Teresa Moran, Emily Howe ...Show all 27 authors... , Linnea E. Fulton, Hillary E. Mulvey, Lindsay A. Bernardo, Farhiya Mohamoud, Norikatsu Miyoshi, Paul A. VanderLaan, Daniel Botelho Costa, Pasi Antero Janne, Darrell R. Borger, Sridhar Ramaswamy, Toshi Shioda, Anthony John Iafrate, Gad Getz, Charles M. Rudin, Mari Mino-Kenudson, Jeffrey Adam Engelman; Show fewer authors
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer.
Nat. Commun. 6:6377.1-6377.10(2015) PubMed=25964297; DOI=10.1158/1078-0432.CCR-15-0560; PMCID=PMC4587765
Matthew J. Niederst, Hai-Chuan Hu, Hillary E. Mulvey, Elizabeth L. Lockerman, Angel R. Garcia, Zofia Piotrowska, Lecia VanDam Sequist, Jeffrey Adam Engelman;
The allelic context of the C797S mutation acquired upon treatment with third-generation EGFR inhibitors impacts sensitivity to subsequent treatment strategies.
Clin. Cancer Res. 21:3924-3933(2015) PubMed=26828195; DOI=10.1038/nm.4040; PMCID=PMC4900892
Aaron Nathaniel Hata, Matthew J. Niederst, Hannah Linn Archibald, Maria Gomez-Caraballo, Faria Madeena Siddiqui, Hillary E. Mulvey, Yosef E. Maruvka, Fei Ji, Hyo-eun Carrie Bhang, Viveksagar Krishnamurthy Radhakrishna, Giulia Siravegna ...Show all 30 authors... , Hai-Chuan Hu, Sana Raoof, Elizabeth L. Lockerman, Anuj Kalsy, Dana Lee, Celina L. Keating, David A. Ruddy, Leah J. Damon, Adam S. Crystal, Carlotta Costa, Zofia Piotrowska, Alberto Bardelli, Anthony John Iafrate, Ruslan I. Sadreyev, Frank Stegmeier, Gad Getz, Lecia VanDam Sequist, Anthony C. Faber, Jeffrey Adam Engelman; Show fewer authors
Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition.
Nat. Med. 22:262-269(2016) |
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