Cellosaurus cell line SUM149-Luc (CVCL

Cellosaurus SUM149-Luc (CVCL_DH44)

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Cell line name

SUM149-Luc

Accession

CVCL_DH44

Resource Identification Initiative

To cite this cell line use: SUM149-Luc (RRID:CVCL_DH44)

Comments

Group: Triple negative breast cancer (TNBC) cell line.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.

Sequence variations

Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:1100; BRCA1; Simple; p.Pro724Leufs*12 (c.2169delT) (p.Asn723fs*13) (2288delT); Zygosity=Hemizygous (from parent cell line).
Mutation; HGNC; HGNC:3373; EP300; Simple; c.4025+26_4025+30 (c.5224+28del3); Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Met237Ile (c.711G>A); ClinVar=VCV000142714; Zygosity=Unspecified (from parent cell line).

Disease

Breast inflammatory carcinoma (NCIt: C4001)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_3422 (SUM149PT)
Children:

CVCL_DH45 (SUM149-Luc/MA1)

CVCL_DH46 (SUM149-Luc/MA2)

Sex of cell

Female

Age at sampling

40Y