Cellosaurus logo
expasy logo

Cellosaurus SUM149-Luc (CVCL_DH44)

[Text version]
Cell line name SUM149-Luc
Accession CVCL_DH44
Resource Identification Initiative To cite this cell line use: SUM149-Luc (RRID:CVCL_DH44)
Comments Group: Triple negative breast cancer (TNBC) cell line.
Transfected with: UniProtKB; P08659; Firefly luciferase.
Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 1100; BRCA1; Simple; p.Pro724Leufs*12 (c.2169delT) (p.Asn723fs*13) (2288delT); Zygosity=Hemizygous (from parent cell line).
  • Mutation; HGNC; 3373; EP300; Simple; c.4025+26_4025+30 (c.5224+28del3); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Met237Ile (c.711G>A); ClinVar=VCV000142714; Zygosity=Unspecified (from parent cell line).
Disease Breast inflammatory carcinoma (NCIt: C4001)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3422 (SUM149PT)
CVCL_DH45 (SUM149-Luc/MA1)CVCL_DH46 (SUM149-Luc/MA2)
Sex of cell Female
Age at sampling 40Y
Category Cancer cell line

PubMed=20229045; DOI=10.1007/s10585-010-9321-4
Singh B., Cook K.R., Martin C., Huang E.H., Mosalpuria K., Krishnamurthy S., Cristofanilli M., Lucci A.
Evaluation of a CXCR4 antagonist in a xenograft mouse model of inflammatory breast cancer.
Clin. Exp. Metastasis 27:233-240(2010)

PubMed=25279830; DOI=10.1371/journal.pone.0109487
Singh B., Shamsnia A., Raythatha M.R., Milligan R.D., Cady A.M., Madan S., Lucci A.
Highly adaptable triple-negative breast cancer cells as a functional model for testing anticancer agents.
PLoS ONE 9:E109487-E109487(2014)

Cell line databases/resources cancercelllines; CVCL_DH44
Encyclopedic resources Wikidata; Q54970828
Gene expression databases GEO; GSM1463862
Entry history
Entry creation13-Jul-2016
Last entry update05-Oct-2023
Version number15