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Cellosaurus SVpgC2a (CVCL_DG34)

[Text version]
Cell line name SVpgC2a
Accession CVCL_DG34
Resource Identification Initiative To cite this cell line use: SVpgC2a (RRID:CVCL_DG34)
Comments Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Oral cavity, buccal mucosa; UBERON=UBERON_0006956.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_DH25 (SVpgC2a-FOXM1B)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=7586160; DOI=10.1093/carcin/16.10.2515
Prabha S. Kulkarni, Kristina Sundqvist, Christer Betsholtz, Petter Hoglund, Klas G. Wiman, Boris Zhivotovsky, Federico Bertolero, Yun Liu, Roland C. Grafstrom;
Characterization of human buccal epithelial cells transfected with the simian virus 40 T-antigen gene.
Carcinogenesis 16:2515-2521(1995)

PubMed=11377230; DOI=10.1016/S1368-8375(00)00089-0
Annette Hansson, Balvinder K. Bloor, Ylva Haig, Peter R. Morgan, Jan Ekstrand, Roland C. Grafstrom;
Expression of keratins in normal, immortalized and malignant oral epithelia in organotypic culture.
Oral Oncol. 37:419-430(2001)

PubMed=15651925; DOI=10.1177/026119290403200412
Claudia A. Staab, Martin Vondracek, Hipolito Custodio, Katarina Johansson, Jan Anders Nilsson, Peter Morgan, Jan-Olov Hoog, Ian Anthony Cotgreave, Roland C. Grafstrom;
Modelling of normal and premalignant oral tissue by using the immortalised cell line, SVpgC2a: a review of the value of the model.
Altern. Lab. Anim. 32:401-405(2004)

PubMed=18186669; DOI=10.1177/026119290703500603
Rebecca Ceder, Marina Merne, Claudia A. Staab, Jan Anders Nilsson, Jan-Olov Hoog, Dirk Dressler, Karin Engelhart, Roland C. Grafstrom;
The application of normal, SV40 T-antigen-immortalised and tumour-derived oral keratinocytes, under serum-free conditions, to the study of the probability of cancer progression as a result of environmental exposure to chemicals.
Altern. Lab. Anim. 35:621-639(2007)

PubMed=19287496; DOI=10.1371/journal.pone.0004849; PMCID=PMC2654098
Emilios Gemenetzidis, Amrita Bose, Adeel M. Riaz, Tracy Chaplin, Bryan D. Young, Muhammad Ali, David Sugden, Johanna K. Thurlow, Sok-Ching Cheong, Soo-Hwang Teo, Hong Wan, Ahmad Waseem, Eric Kenneth Parkinson ...Show all 15 authors... , Farida Fortune, Muy-Teck Teh; Show fewer authors
FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation.
PLoS ONE 4:e4849.1-e4849.18(2009)

CLPUB00346
Rebecca Ceder;
Cancer biomarker discovery by in vitro systems biology.
Thesis PhD (2011); Karolinska Institutet; Stockholm; Sweden

Cross-references
Encyclopedic resources Wikidata; Q54971035
Gene expression databases GEO; GSM190619
GEO; GSM190620
GEO; GSM298193
GEO; GSM966935
GEO; GSM966936
GEO; GSM966937
Entry history
Entry creation13-Jul-2016
Last entry update10-Apr-2025
Version number7