Cellosaurus cell line hFOB/ER9 (CVCL

Cellosaurus hFOB/ER9 (CVCL_DG20)

Cross-references
Cell line name	hFOB/ER9
Accession	CVCL_DG20
Resource Identification Initiative	To cite this cell line use: hFOB/ER9 (RRID:CVCL_DG20)
Comments	Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3467; ESR1. Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58). Derived from site: In situ; Fetal bone, limb; UBERON=UBERON_0002428. Cell type: Osteoblast; CL=CL_0000062.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_3708 (hFOB 1.19)
Sex of cell	Female
Age at sampling	Fetus
Category	Conditionally immortalized cell line
Publications	PubMed=8904314; DOI=10.1002/jcb.240590209 Steven A. Harris, Kimberly R. Tau, Robert J. Enger, David O. Toft, B. Lawrence Riggs, Thomas C. Spelsberg; Estrogen response in the hFOB 1.19 human fetal osteoblastic cell line stably transfected with the human estrogen receptor gene. J. Cell. Biochem. 59:193-201(1995) PubMed=12210717; DOI=10.1002/jcb.10259 Malayannan Subramaniam, Syed M. Jalal, David J. Rickard, Steven A. Harris, Mark E. Bolander, Thomas C. Spelsberg; Further characterization of human fetal osteoblastic hFOB 1.19 and hFOB/ER alpha cells: bone formation in vivo and karyotype analysis using multicolor fluorescent in situ hybridization. J. Cell. Biochem. 87:9-15(2002)
Encyclopedic resources	Wikidata; Q54883301
Entry history
Entry creation	13-Jul-2016
Last entry update	14-Aug-2025
Version number	14