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Cellosaurus AGE1.HN.AAT (CVCL_DF61)

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Cell line name AGE1.HN.AAT
Accession CVCL_DF61
Resource Identification Initiative To cite this cell line use: AGE1.HN.AAT (RRID:CVCL_DF61)
Comments From: ProBioGen AG; Berlin; Germany.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:8941; SERPINA1.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03281; Human adenovirus C serotype 5 pIX.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5 (Note=E1A/E1B).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_DF60 (AGE1.HN)
Category Transformed cell line
Publications

PubMed=22373196; DOI=10.1186/1753-6561-5-S8-P78; PMCID=PMC3285003
Sebastian Scholz, Miriam Luebbecke, Alexander Rath, Eva Skerhutt, Thomas Rose, Heino Buntemeyer, Thomas Scheper, Udo Reichl, Thomas Noll;
Characterization of the human AGE1.HN cell line: a systems biology approach.
BMC Proc. 5 Suppl. 8:P78-P78(2011)

PubMed=22373444; DOI=10.1186/1753-6561-5-S8-P87; PMCID=PMC3284914
Eva Skerhutt, Sebastian Scholz, Jens Niklas, Alexander Rath, Oscar Platas-Barradas, Uwe Jandt, Volker Sandig, Thomas Rose, Ralf Portner, Udo Reichl, An-Ping Zeng ...Show all 13 authors... , Elmar Heinzle, Thomas Noll; Show fewer authors
Characterisation of cultivation of the human cell line AGE1.HN.AAT.
BMC Proc. 5 Suppl. 8:P87-P87(2011)

PubMed=21842438; DOI=10.1007/s00253-011-3526-6
Jens Niklas, Christian Priesnitz, Thomas Rose, Volker Sandig, Elmar Heinzle;
Primary metabolism in the new human cell line AGE1.HN at various substrate levels: increased metabolic efficiency and alpha1-antitrypsin production at reduced pyruvate load.
Appl. Microbiol. Biotechnol. 93:1637-1650(2012)

DOI=10.1002/elsc.201200111
Susann Freund, Alexander Rath, Oscar Platas-Barradas, Eva Skerhutt, Sebastian Scholz, Jens Niklas, Volker Sandig, Thomas Rose, Elmar Heinzle, Thomas Noll, Ralf Portner ...Show all 13 authors... , An-Ping Zeng, Udo Reichl; Show fewer authors
Batch-to-batch variability of two human designer cell lines - AGE1.HN and AGE1.HN.AAT - carried out by different laboratories under defined culture conditions using a mathematical model.
Eng. Life Sci. 13:580-592(2013)

Cross-references
Encyclopedic resources Wikidata; Q54748640
Entry history
Entry creation13-Jul-2016
Last entry update27-Nov-2025
Version number9