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Cellosaurus AGE1.HN (CVCL_DF60)

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Cell line name AGE1.HN
Accession CVCL_DF60
Resource Identification Initiative To cite this cell line use: AGE1.HN (RRID:CVCL_DF60)
Comments From: ProBioGen AG; Berlin; Germany.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03281; Human adenovirus C serotype 5 pIX.
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5 (Note=E1A/E1B).
Omics: Proteomics; Subcellular; Mitochondrion; 2DE-MS.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_DF61 (AGE1.HN.AAT)
Category Transformed cell line
Web pages Provider; ProBioGen; -; https://www.probiogen.de/virus-production-cell-lines.html
Publications

PubMed=21188421; DOI=10.1007/s00449-010-0502-y; PMCID=PMC3092918
Jens Niklas, Eva Skerhutt, Volker Sandig, Thomas Noll, Elmar Heinzle;
Quantitative characterization of metabolism and metabolic shifts during growth of the new human cell line AGE1.HN using time resolved metabolic flux analysis.
Bioprocess Biosyst. Eng. 34:533-545(2011)

PubMed=22373415; DOI=10.1186/1753-6561-5-S8-P86; PMCID=PMC3284977
Eva Skerhutt, Sebastian Scholz, Volker Sandig, Raimund Hoffrogge, Thomas Noll;
Analysis of the mitochondrial subproteome of the human cell line AGE1.HN - a contribution to a systems biology approach.
BMC Proc. 5 Suppl. 8:P86-P86(2011)

PubMed=21842438; DOI=10.1007/s00253-011-3526-6
Jens Niklas, Christian Priesnitz, Thomas Rose, Volker Sandig, Elmar Heinzle;
Primary metabolism in the new human cell line AGE1.HN at various substrate levels: increased metabolic efficiency and alpha1-antitrypsin production at reduced pyruvate load.
Appl. Microbiol. Biotechnol. 93:1637-1650(2012)

DOI=10.1002/elsc.201200111
Susann Freund, Alexander Rath, Oscar Platas-Barradas, Eva Skerhutt, Sebastian Scholz, Jens Niklas, Volker Sandig, Thomas Rose, Elmar Heinzle, Thomas Noll, Ralf Portner ...Show all 13 authors... , An-Ping Zeng, Udo Reichl; Show fewer authors
Batch-to-batch variability of two human designer cell lines - AGE1.HN and AGE1.HN.AAT - carried out by different laboratories under defined culture conditions using a mathematical model.
Eng. Life Sci. 13:580-592(2013)

Cross-references
Encyclopedic resources Wikidata; Q54748639
Entry history
Entry creation13-Jul-2016
Last entry update27-Nov-2025
Version number10