Cellosaurus cell line HT-1080 NucLight Green (CVCL

Cross-references
Cell line name	HT-1080 NucLight Green
Accession	CVCL_DF43
Resource Identification Initiative	To cite this cell line use: HT-1080 NucLight Green (RRID:CVCL_DF43)
Comments	Population: Caucasian. Characteristics: Stably expresses a non-perturbing nuclear restricted green fluorescent label. Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Discontinued: Sartorius/Essen Biosciences; Catalog number 4486. Derived from site: In situ; Bone, pelvis, acetabulum; UBERON=UBERON_0001269.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132Cys (c.394C>T); ClinVar=VCV000375891; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Disease	Fibrosarcoma (NCIt: C3043) Fibrosarcoma (ORDO: Orphanet_2030)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0317 (HT-1080)
Sex of cell	Male
Age at sampling	35Y
Category	Cancer cell line
Cell line databases/resources	cancercelllines; CVCL_DF43
Encyclopedic resources	Wikidata; Q54896498
Entry history
Entry creation	13-Jul-2016
Last entry update	14-Aug-2025
Version number	22