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Cellosaurus RTgutGC (CVCL_DE13)

[Text version]
Cell line name RTgutGC
Synonyms Rainbow Trout gut Germany Canada
Accession CVCL_DE13
Resource Identification Initiative To cite this cell line use: RTgutGC (RRID:CVCL_DE13)
Comments Group: Fish cell line.
Doubling time: 2.9 days (PubMed=34205481).
Derived from site: In situ; Intestine; UBERON=UBERON_0000160.
Cell type: Epithelial cell of intestine; CL=CL_0002563.
Species of origin Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri) (NCBI Taxonomy: 8022)
Sex of cell Female
Age at sampling Age unspecified
Category Spontaneously immortalized cell line

Kawano A.
Developing and characterizing a salmonid intestinal epithelial cell line for use in studies of inflammation in the fish gastrointestinal tract.
Thesis PhD (2009), University of Waterloo, Canada

PubMed=20420918; DOI=10.1016/j.fsi.2010.04.007
Kawano A., Kales S.C., Fujiki K., DeWitte-Orr S.J., Dixon B., Lee L.E.J., Bols N.C.
A comparison of rainbow trout cell lines for their expression of the major histocompatibility complex genes and the induction of beta-2-microglobulin by dsRNA.
Fish Shellfish Immunol. 29:312-318(2010)

Kawano A., Haiduk C., Schirmer K., Hanner R., Lee L.E.J., Dixon B., Bols N.C.
Development of a rainbow trout intestinal epithelial cell line and its response to lipopolysaccharide.
Aquac. Nutr. 17:e241-e252(2011)

PubMed=24357037; DOI=10.1007/s11626-013-9720-3
Vo N.T.K., Bufalino M.R., Hartlen K.D., Kitaev V., Lee L.E.J.
Cytotoxicity evaluation of silica nanoparticles using fish cell lines.
In Vitro Cell. Dev. Biol. Anim. 50:427-438(2014)

PubMed=28251411; DOI=10.1007/s10565-017-9385-x
Minghetti M., Drieschner C., Bramaz N., Schug H., Schirmer K.
A fish intestinal epithelial barrier model established from the rainbow trout (Oncorhynchus mykiss) cell line, RTgutGC.
Cell Biol. Toxicol. 33:539-555(2017)

PubMed=28374170; DOI=10.1007/s11626-017-0142-5
Bols N.C., Pham P.H., Dayeh V.R., Lee L.E.J.
Invitromatics, invitrome, and invitroomics: introduction of three new terms for in vitro biology and illustration of their use with the cell lines from rainbow trout.
In Vitro Cell. Dev. Biol. Anim. 53:383-405(2017)

PubMed=31256301; DOI=10.1007/s10616-019-00327-0
Drieschner C., Vo N.T.K., Schug H., Burkard M., Bols N.C., Renaud P., Schirmer K.
Improving a fish intestinal barrier model by combining two rainbow trout cell lines: epithelial RTgutGC and fibroblastic RTgutF.
Cytotechnology 71:835-848(2019)

PubMed=33053677; DOI=10.3390/pathogens9100833
Pham P.H., Misk E., Papazotos F., Jones G., Polinski M.P., Contador E., Russell S., Garver K.A., Lumsden J.S., Bols N.C.
Screening of fish cell lines for piscine orthoreovirus-1 (PRV-1) amplification: identification of the non-supportive PRV-1 invitrome.
Pathogens 9:833.1-833.25(2020)

PubMed=34205481; DOI=10.3390/cells10061555
Pasquariello R., Verdile N., Pavlovic R., Panseri S., Schirmer K., Brevini T.A.L., Gandolfi F.
New stable cell lines derived from the proximal and distal intestine of rainbow trout (Oncorhynchus mykiss) retain several properties observed in vivo.
Cells 10:1555.1-1555.17(2021)

Encyclopedic resources Wikidata; Q54951405
Entry history
Entry creation13-Jul-2016
Last entry update05-Oct-2023
Version number10