Cellosaurus H1L7.5c3 (CVCL_DC25)
| Cell line name | H1L7.5c3 |
|---|---|
| Accession | CVCL_DC25 |
| Resource Identification Initiative | To cite this cell line use: H1L7.5c3 (RRID:CVCL_DC25) |
| Comments | Biotechnology: Cell line developed for CALUX (Chemically Activated LUciferase eXpression) bioassay. CALUX is used for rapid screening of samples for the presence of dioxin/TCDD-like compounds and AhR agonists/antagonists. Characteristics: Acts through the activation of a luciferase reporter gene under the control of dioxin-response elements (DREs). Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase. Derived from site: In situ; Liver; UBERON=UBERON_0002107. |
| Disease | Hepatocellular carcinoma of the mouse (NCIt: C38756) |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C57L/J. |
| Hierarchy | Parent: CVCL_0328 (Hepa-1c1c7) |
| Sex of cell | Female |
| Age at sampling | Age unspecified |
| Category | Cancer cell line |
| Publications | PubMed=26366531; DOI=10.1021/acs.est.5b02906; PMCID=PMC4772899 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54871991 |
| Entry history | |
| Entry creation | 13-Jul-2016 |
| Last entry update | 27-Nov-2025 |
| Version number | 13 |