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Cellosaurus CHO WCL2 (CVCL_DC12)

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Cell line name CHO WCL2
Synonyms WCL2; WCL-2
Accession CVCL_DC12
Resource Identification Initiative To cite this cell line use: CHO WCL2 (RRID:CVCL_DC12)
Comments Genetic integration: Method=Transfection; Gene=MGI; MGI:94890; Dhfr.
Genetic integration: Method=Transfection; Gene=MGI; MGI:95824; Nr3c1.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_1977 (CHO-DXB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=2243084; DOI=10.1016/S0021-9258(17)30478-7
Edwin R. Sanchez, Margaret A. Hirst, Lawrence C. Scherrer, Hsin-Yi Tang, Michael James Welsh, Jeffrey M. Harmon, S. Stoney Simons Jr., Gordon M. Ringold, William Brewster Pratt;
Hormone-free mouse glucocorticoid receptors overexpressed in Chinese hamster ovary cells are localized to the nucleus and are associated with both hsp70 and hsp90.
J. Biol. Chem. 265:20123-20130(1990)

PubMed=2019585; DOI=10.1016/S0021-9258(20)89482-4
Jack Edward Bodwell, Eduardo Orti, James M. Coull, Darryl J.C. Pappin, Lynda I. Smith, Fiona Swift;
Identification of phosphorylated sites in the mouse glucocorticoid receptor.
J. Biol. Chem. 266:7549-7555(1991)

Cross-references
Encyclopedic resources Wikidata; Q54993621
Entry history
Entry creation13-Jul-2016
Last entry update10-Apr-2025
Version number10