Cellosaurus cell line HPK-1A-ras (CVCL

Cellosaurus HPK-1A-ras (CVCL_D891)

Cross-references
Cell line name	HPK-1A-ras
Synonyms	HPK-1A/ras; HPK1A-ras; KiMSV/HPK-1A; K-ras/HPK-1A
Accession	CVCL_D891
Resource Identification Initiative	To cite this cell line use: HPK-1A-ras (RRID:CVCL_D891)
Comments	Virology: Contains several complete HPV16 genomes arranged in a head-to-tail fashion and integrated at a single chromosomal site. Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16). Transformant: NCBI_TaxID; 11808; Kirsten murine sarcoma virus (Ki-MSV). Derived from site: In situ; Foreskin, skin, epidermis; UBERON=UBERON_0001471+UBERON_0001003. Cell type: Keratinocyte; CL=CL_0000312.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_D890 (HPK-1A)
Sex of cell	Male
Category	Transformed cell line
Publications	PubMed=2556855; DOI=10.1016/0042-6822(89)90595-3 Matthias Durst, Dan Gallahan, Gilbert Jay, Johng Sik Rhim; Glucocorticoid-enhanced neoplastic transformation of human keratinocytes by human papillomavirus type 16 and an activated ras oncogene. Virology 173:767-771(1989) DOI=10.1007/978-1-4612-0411-4_3 B. Lynn Allen-Hoffmann, Nader Sheibani, Jill S. Hatfield, Johng Sik Rhim; Use of immortalized human keratinocytes for the study of squamous differentiation and mutagenesis. (In book chapter) Neoplastic transformation in human cell system. Mechanism of carcinogenesis; Rhim, Johng Sik & Dritschilo, Anatoly (eds.); pp.25-34; Humana Press; New York; USA (1990) PubMed=1742725 Janet Henderson, Michael Sebag, Johng Sik Rhim, David Goltzman, Richard Kremer; Dysregulation of parathyroid hormone-like peptide expression and secretion in a keratinocyte model of tumor progression. Cancer Res. 51:6521-6528(1991)
Anatomy/cell type resources	BTO; BTO_0005275
Encyclopedic resources	Wikidata; Q54890292
Entry history
Entry creation	22-Oct-2012
Last entry update	19-Dec-2024
Version number	13