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Cellosaurus RAW 264.7 Sting1 KO + Sting1 (CVCL_D7F4)

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Cell line name RAW 264.7 Sting1 KO + Sting1
Synonyms RAW 264.7 STING KO + mouse STING (WT)
Accession CVCL_D7F4
Resource Identification Initiative To cite this cell line use: RAW 264.7 Sting1 KO + Sting1 (RRID:CVCL_D7F4)
Comments Knockout cell: Method=CRISPR/Cas9; MGI; MGI:1919762; Sting1.
Genetic integration: Method=PiggyBac transposition; Gene=MGI; MGI:1919762; Sting1.
Genetic integration: Method=PiggyBac transposition; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 11788; Abelson mouse leukemia virus (AbMuLV).
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: Macrophage; CL=CL_0000235.
Disease Mouse leukemia (NCIt: C21604)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_D7F3 (RAW 264.7 Sting1 KO)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Publications

PubMed=39812709; DOI=10.1083/jcb.202310150; PMCID=PMC11734622
Amanda Bentley-DeSousa, Agnes Roczniak-Ferguson, Shawn M. Ferguson;
A STING-CASM-GABARAP pathway activates LRRK2 at lysosomes.
J. Cell Biol. 224:e202310150.1-e202310150.25(2025)

Entry history
Entry creation10-Sep-2024
Last entry update27-Nov-2025
Version number3