• Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Lys (c.1798_1799delGTinsAA); ClinVar=VCV000375941; Zygosity=Heterozygous (PubMed=21880213; PubMed=23489693).
  
• Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Trp383Cys (c.1149G>T); Zygosity=Unspecified (PubMed=23489693).
  

PubMed=21880213
Paola Zanna, Immacolata Maida, Mari Carmen Turpin Sevilla, Francesco Claudio Susca, Raffaele Filotico, Marcella Arciuli, Nicoletta Cassano, Gino Antonio Vena, Rosa Cicero, Gabriella Guida;
Molecular characterization of novel melanoma cell lines.
J. Biol. Regul. Homeost. Agents 25:239-247(2011)

PubMed=23489693
Paola Zanna, Immacolata Maida, Claudia Grieco, Stefania Guida, Mari Carmen Turpin Sevilla, Simona De Summa, Stefania Tommasi, Gino Antonio Vena, Raffaele Filotico, Gabriella Guida;
Three novel human sporadic melanoma cell lines: signaling pathways controlled by MC1R, BRAF and beta-catenins.
J. Biol. Regul. Homeost. Agents 27:131-141(2013)

DOI=10.1186/1479-5876-12-S1-P7
Amalia Azzariti, Letizia Porcelli, Anna Elisa Quatrale, Letizia Sidella, Rosa Maria Iacobazzi, Gabriella Guida, Immacolata Maida, Tiziana Cocco, Anna Ferretta, Sabino Strippoli, Stefania Guida ...Show all 14 authors... , Stefania Tommasi, Angelo Paradiso, Michele Guida; Show fewer authors
Barasertib: a novel approach for the treatment of metastatic melanoma.
J. Transl. Med. 12 Suppl. 1:P7-P7(2014)

PubMed=25623468; DOI=10.1186/s12967-015-0385-4; PMCID=PMC4314759
Letizia Porcelli, Gabriella Guida, Anna Elisa Quatrale, Tiziana Cocco, Letizia Sidella, Immacolata Maida, Rosa Maria Iacobazzi, Anna Ferretta, Diana Antonella Stolfa, Sabino Strippoli, Stefania Guida ...Show all 14 authors... , Stefania Tommasi, Michele Guida, Amalia Azzariti; Show fewer authors
Aurora kinase B inhibition reduces the proliferation of metastatic melanoma cells and enhances the response to chemotherapy.
J. Transl. Med. 13:26.1-26.13(2015)

PubMed=27540956; DOI=10.1111/pcmr.12516
Michele Guida, Sabino Strippoli, Anna Ferretta, Nicola Bartolomeo, Letizia Porcelli, Immacolata Maida, Amalia Azzariti, Stefania Tommasi, Claudia Grieco, Stefania Guida, Anna Albano ...Show all 13 authors... , Vito Lorusso, Gabriella Guida; Show fewer authors
Detrimental effects of melanocortin-1 receptor (MC1R) variants on the clinical outcomes of BRAF V600 metastatic melanoma patients treated with BRAF inhibitors.
Pigment Cell Melanoma Res. 29:679-687(2016)