| Cell line name |
A99 |
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| Synonyms |
a 99 |
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| Accession |
CVCL_D699 |
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| Resource Identification Initiative |
To cite this cell line use: A99 (RRID:CVCL_D699) |
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| Comments |
Characteristics: Established from a nude mice xenograft. Tumorigenic (PubMed=21768923).
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107. |
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| Sequence variations |
- Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Leu (c.34_35GG>CT) (c.34_35delinsCT); Zygosity=Homozygous (PubMed=21768923).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser127Thr (c.379T>A); ClinVar=VCV000824232; Zygosity=Homozygous (PubMed=21768923).
|
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| Disease |
Pancreatic small cell carcinoma (NCIt: C95583)
Neuroendocrine tumor of pancreas (ORDO: Orphanet_97253) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Sex of cell |
Female |
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| Age at sampling |
60Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=21768923; DOI=10.1097/MPA.0b013e3182207a58; PMCID=PMC3180880
Shinichi Yachida, Yi Zhong, Raul Patrascu, Meghan B. Davis, Laura A. Morsberger, Constance A. Griffin, Ralph H. Hruban, Daniel Laheru, Christine A. Iacobuzio-Donahue;
Establishment and characterization of a new cell line, A99, from a primary small cell carcinoma of the pancreas.
Pancreas 40:905-910(2011) DOI=10.4172/2324-9293.1000104
Markus Udo Wagenhauser, Felix Ruckert, Marco Niedergethmann, Robert Grutzmann, Hans-Detlev Saeger;
Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines.
Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013) PubMed=29765522; DOI=10.18632/oncotarget.24930; PMCID=PMC5940407
Akihiro Ohmoto, Masami Suzuki, Erina Takai, Hirofumi Rokutan, Yuko Fujiwara, Chigusa Morizane, Kazuyoshi Yanagihara, Tatsuhiro Shibata, Shinichi Yachida;
Establishment of preclinical chemotherapy models for gastroenteropancreatic neuroendocrine carcinoma.
Oncotarget 9:21086-21099(2018) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_D699
|
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| Encyclopedic resources |
Wikidata; Q54607556
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| Polymorphism and mutation databases |
Cosmic; 1767220
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| Entry history |
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| Entry creation | 22-Oct-2012 |
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| Last entry update | 19-Dec-2024 |
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| Version number | 17 |
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