ID   A99
AC   CVCL_D699
SY   a 99
DR   cancercelllines; CVCL_D699
DR   Cosmic; 1767220
DR   Wikidata; Q54607556
RX   DOI=10.4172/2324-9293.1000104;
RX   PubMed=21768923;
RX   PubMed=29765522;
CC   Characteristics: Established from a nude mice xenograft. Tumorigenic (PubMed=21768923).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Leu (c.34_35GG>CT) (c.34_35delinsCT); Zygosity=Homozygous (PubMed=21768923).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ser127Thr (c.379T>A); ClinVar=VCV000824232; Zygosity=Homozygous (PubMed=21768923).
CC   Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
DI   NCIt; C95583; Pancreatic small cell carcinoma
DI   ORDO; Orphanet_97253; Neuroendocrine tumor of pancreas
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   60Y
CA   Cancer cell line
DT   Created: 22-10-12; Last updated: 19-12-24; Version: 17
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RX   DOI=10.4172/2324-9293.1000104;
RA   Wagenhauser M.U., Ruckert F., Niedergethmann M., Grutzmann R.,
RA   Saeger H.-D.;
RT   "Distribution of characteristic mutations in native ductal
RT   adenocarcinoma of the pancreas and pancreatic cancer cell lines.";
RL   Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013).
//
RX   PubMed=21768923; DOI=10.1097/MPA.0b013e3182207a58; PMCID=PMC3180880;
RA   Yachida S., Zhong Y., Patrascu R., Davis M.B., Morsberger L.A.,
RA   Griffin C.A., Hruban R.H., Laheru D., Iacobuzio-Donahue C.A.;
RT   "Establishment and characterization of a new cell line, A99, from a
RT   primary small cell carcinoma of the pancreas.";
RL   Pancreas 40:905-910(2011).
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RX   PubMed=29765522; DOI=10.18632/oncotarget.24930; PMCID=PMC5940407;
RA   Ohmoto A., Suzuki M., Takai E., Rokutan H., Fujiwara Y., Morizane C.,
RA   Yanagihara K., Shibata T., Yachida S.;
RT   "Establishment of preclinical chemotherapy models for
RT   gastroenteropancreatic neuroendocrine carcinoma.";
RL   Oncotarget 9:21086-21099(2018).
//