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Cellosaurus mtop2beta-6 (CVCL_D634)

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Cell line name mtop2beta-6
Accession CVCL_D634
Resource Identification Initiative To cite this cell line use: mtop2beta-6 (RRID:CVCL_D634)
Comments Knockout cell: Method=Homologous recombination; MGI; MGI:98791; Top2b.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Transformed cell line
Publications

PubMed=10570059; DOI=10.1124/mol.56.6.1309
Fiona Errington, Elaine Willmore, Michael J. Tilby, Li-Geng Li, Gloria C. Li, Wei Li, Bruce Charles Baguley, Caroline Ann Austin;
Murine transgenic cells lacking DNA topoisomerase IIbeta are resistant to acridines and mitoxantrone: analysis of cytotoxicity and cleavable complex formation.
Mol. Pharmacol. 56:1309-1316(1999)

Cross-references
Encyclopedic resources Wikidata; Q54907015
Entry history
Entry creation22-Oct-2012
Last entry update14-Aug-2025
Version number10