ID   mtop2beta-6
AC   CVCL_D634
DR   Wikidata; Q54907015
RX   PubMed=10570059;
CC   Knockout cell: Method=Homologous recombination; MGI; MGI:98791; Top2b.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
CC   Cell type: Fibroblast; CL=CL_0000057.
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Sex unspecified
AG   Embryo
CA   Transformed cell line
DT   Created: 22-10-12; Last updated: 14-08-25; Version: 10
//
RX   PubMed=10570059; DOI=10.1124/mol.56.6.1309;
RA   Errington, Fiona
RA   Willmore, Elaine
RA   Tilby, Michael J.
RA   Li, Li-Geng
RA   Li, Gloria C.
RA   Li, Wei
RA   Baguley, Bruce Charles
RA   Austin, Caroline Ann
RT   "Murine transgenic cells lacking DNA topoisomerase IIbeta are
RT   resistant to acridines and mitoxantrone: analysis of cytotoxicity and
RT   cleavable complex formation.";
RL   Mol. Pharmacol. 56:1309-1316(1999).
//