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Cellosaurus A172/TMZ (CVCL_D5ZN)

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Cell line name A172/TMZ
Accession CVCL_D5ZN
Resource Identification Initiative To cite this cell line use: A172/TMZ (RRID:CVCL_D5ZN)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_72564; Temozolomide (TMZ).
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Gene deletion; HGNC; HGNC:9588; PTEN; Zygosity=Homozygous (from parent cell line).
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1539; CBFB; Name(s)=ABL1-CBFB (from parent cell line).
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0131 (A-172)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=34036375; DOI=10.3892/mmr.2021.12172; PMCID=PMC8170197
Yi-Qiang Cao, Wen-Ying Chai, Yong-Gang Wang, Dang Tang, Dong-Chuan Shao, Hai Song, Jiang Long;
lncRNA TUG1 inhibits the cancer stem cell-like properties of temozolomide-resistant glioma cells by interacting with EZH2.
Mol. Med. Rep. 24:533.1-533.10(2021)

Cross-references
Encyclopedic resources Wikidata; Q127378810
Entry history
Entry creation02-May-2024
Last entry update19-Dec-2024
Version number3