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Cellosaurus (CVCL_D5IJ)

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Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Part of: COSMIC cell lines project.
Population: Japanese.
Doubling time: 29 hours (PubMed=3022030).
Microsatellite instability: Stable (MSS) (Sanger).
Omics: Genomics; DNA methylation analysis.
Omics: Genomics; Whole exome sequencing.
Omics: Phenotyping; Drug screening.
Omics: Proteomics.
Omics: Proteomics; Quantitative.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Omics: Variations; SNP array analysis.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
Genome ancestry Source: PubMed=30894373

Origin% genome
African1.34
Native American0
East Asian, North86.97
East Asian, South5.88
South Asian2.89
European, North2.93
European, South0
Disease Lung small cell carcinoma (NCIt: C4917)
Small cell lung cancer (ORDO: Orphanet_70573)
Species of origin Canis lupus familiaris (Dog) (Canis familiaris) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 63Y
Category Cancer cell line
STR profile Source(s): Cosmic-CLP=713878; RCB=RCB0469

Markers:
AmelogeninX,Y
CSF1PO11
D13S31711
D16S5399
D5S81813
D7S82012
TH019
TPOX8,12
vWA17

Run an STR similarity search on this cell line
Publications





Kurt Neumann, Miguel Beato;
Establishment of rat endometrial cell lines by retroviral mediated transfer of immortalizing and transforming oncogenes.
Oncogene 5:787-794(1990)


William L. Perry 3rd;
Microsatellite deletion mapping on chromosome 10q and mutation analysis of MMAC1, FAS, and MXI1 in human glioblastoma multiforme.
Int. J. Oncol. 12:905-910(1998)


Bo Ahren, Goran Stenman, Ola Nilsson;
A transplantable human carcinoid as model for somatostatin receptor-mediated and amine transporter-mediated radionuclide uptake.
Am. J. Pathol. 158:745-755(2001)




Jpn. J. Cancer Res. 93:667-676(2002)


Chandramohan S. Ishwad, Jonathan W. Jarvik;
Detection and assignment of TP53 mutations in tumor DNA using peptide mass signature genotyping.
Hum. Mutat. 22:158-165(2003)


Jun Cheng, Satoshi Maruyama, Kazufumi Ohshiro, Ichiro Suzuki, Yukiko Hoshina, Takashi Saku;
Establishment and characterization of new cell lines derived from melanotic neuroectodermal tumor of infancy arising in the mandible.
Pathol. Int. 55:331-342(2005)


Sakon Noriki;
Multiple inflammatory cytokine-productive ThyL-6 cell line established from a patient with thymic carcinoma.
Cancer Sci. 99:1778-1784(2008)


Paula D. Bos, Xiang H.-F. Zhang, Cristina Nadal, Wei-Ping Shu, Roger R. Gomis, Don X. Nguyen, Andy J. Minn, Marc Joan van de Vijver, William Levi Gerald, John A. Foekens, Joan Massague;
Genes that mediate breast cancer metastasis to the brain.
Nature 459:1005-1009(2009)



uveal melanoma.
Genes Chromosomes Cancer 50:34-42(2011)


Yasuhiro Takashima, Ge Guo, Remco Loos, Jennifer Nichols, Gabriella Ficz, Felix Krueger, David Oxley, Fatima Santos, James Clarke, William Mansfield, Wolf Reik ...Show all 13 authors... , Paul Bertone, Austin Gerard Smith; Show fewer authors
Resetting transcription factor control circuitry toward ground-state pluripotency in human.
Cell 158:1254-1269(2014)



literature.
Cancer Res. 77:2784-2788(2017)




Cancer Cell 33:386-400.e5(2018)


Ji-Gui Peng, Hao Xu, Jian-Chun Cai;
Establishment and characterization of a new gastric cancer cell line, XGC-1.
Cancer Cell Int. 20:437.1-437.10(2020)


Maryam Alowaysi, Mohammad Al-Shehri, Amani Badkok, Hanouf Attas, Doaa Aboalola, Moayad Baadhaim, Hajar AlZahrani, Mustafa Daghestani, Asima Zia, Khalid AlGhamdi, Asayil AlGhamdi ...Show all 15 authors... , Samer Zakri, Sihem Aouabdi, Jesper Tegner, Khaled N. Alsayegh; Show fewer authors
Generation of iPSC lines (KAIMRCi003A, KAIMRCi003B) from a Saudi patient with Dravet syndrome carrying homozygous mutation in the CPLX1 gene and heterozygous mutation in SCN9A.
Hum. Cell 37:502-510(2024)


Damian Smedley, Lorenz P. Studer, Wei Sun, Dusica Vidovic, Thomas Vierbuchen, Brian S. White, Ka Yee Yeung, Feng Yue, Ting Zhou;
MorPhiC Consortium
MorPhiC Consortium: towards functional characterization of all human genes.
Nature 638:351-359(2025)

Cross-references
Cell line collections (Providers) RCB; RCB0469
Chemistry resources PharmacoDB; LU139_867_2019
PubChem_Cell_line; CVCL_1390
Encyclopedic resources Wikidata; Q54903195
Proteomic databases PRIDE; PXD011896
PRIDE; PXD030304
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number41