Cellosaurus cell line SVG-10B1 (CVCL

Cellosaurus SVG-10B1 (CVCL_D5B6)

Cross-references
Cell line name	SVG-10B1
Synonyms	10B1
Accession	CVCL_D5B6
Resource Identification Initiative	To cite this cell line use: SVG-10B1 (RRID:CVCL_D5B6)
Comments	Virology: Highly permissive for JC virus (JCV) DNA replication and gene expression and supported persistent and stable JCV infection over months in culture (PubMed=24052414). Caution: In contrast to SVG p12 (Cellosaurus=CVCL_3797), this cell line is not contaminated with BK polyomavirus (PubMed=25288626). Derived from site: In situ; Fetal brain; UBERON=UBERON_0006238. Cell type: Astrocyte; CL=CL_0000127.
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_5G14 (SVG)
Sex of cell	Male
Age at sampling	8-12FW
Category	Transformed cell line
Publications	PubMed=24052414; DOI=10.1007/s11481-013-9499-8 Michael W. Ferenczy, Kory R. Johnson, Shannon M. Steinberg, Leslie J. Marshall, Maria Chiara G. Monaco-Kushner, Alexander M. Beschloss, Peter N. Jensen, Eugene O. Major; Clonal immortalized human glial cell lines support varying levels of JC virus infection due to differences in cellular gene expression. J. Neuroimmune Pharmacol. 8:1303-1319(2013) PubMed=25288626; DOI=10.1128/JVI.01600-14; PMCID=PMC4248886 Michael W. Ferenczy, Eugene O. Major; Contamination of SVG p12 cells with BK polyomavirus occurred after deposit in the American Type Culture Collection. J. Virol. 88:12928-12929(2014)
Encyclopedic resources	Wikidata; Q127384339
Entry history
Entry creation	02-May-2024
Last entry update	10-Sep-2024
Version number	2