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Cellosaurus SVG p12 (CVCL_3797)

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Cell line name SVG p12
Synonyms SVGp12; SVG(P12)
Accession CVCL_3797
Resource Identification Initiative To cite this cell line use: SVG p12 (RRID:CVCL_3797)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-8621.
Virology: Contaminated with BK polyomavirus strain UT (PubMed=24760884; PubMed=25288626).
Doubling time: 24-36 hours (Hysigen=TCH-C631).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSVori-).
Derived from site: In situ; Fetal brain; UBERON=UBERON_0006238.
Cell type: Astrocyte; CL=CL_0000127.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_5G14 (SVG)
Sex of cell Male
Age at sampling 8-12FW
Category Transformed cell line
STR profile Source(s): AddexBio=T0005008/4960; ATCC=CRL-8621; Hysigen=TCH-C631

Markers:
AmelogeninX (Hysigen=TCH-C631)
X,Y (AddexBio=T0005008/4960; ATCC=CRL-8621)
CSF1PO10,11,12
D1S165613,15,16,17.3
D2S133819,21,22,24
D3S135815,16,17
D5S81811,12,14
D6S104311,17,18,19
D7S82010,12,13
D8S117912,13,14
D10S124813,14
D12S39115,16,20
D13S3178,13,14
D16S53910,11,12
D18S5114,15,16,18
D19S43313,14.2,15
D21S1129,30
FGA22,24,25
Penta D7,11,12,13
Penta E11,12,14,18
TH016,7,9,9.3 (AddexBio=T0005008/4960; Hysigen=TCH-C631)
6,7,9.3 (ATCC=CRL-8621)
TPOX8,10,11
vWA15,16,18,19

Run an STR similarity search on this cell line
Web pages Info; The Scientist; -; https://www.the-scientist.com/virus-detected-in-human-cell-line-37377
Publications

Patent=US4707448
Eugene O. Major;
Immortal line of human fetal glial cells.
Patent number US4707448, 17-Nov-1987

PubMed=24052414; DOI=10.1007/s11481-013-9499-8
Michael W. Ferenczy, Kory R. Johnson, Shannon M. Steinberg, Leslie J. Marshall, Maria Chiara G. Monaco-Kushner, Alexander M. Beschloss, Peter N. Jensen, Eugene O. Major;
Clonal immortalized human glial cell lines support varying levels of JC virus infection due to differences in cellular gene expression.
J. Neuroimmune Pharmacol. 8:1303-1319(2013)

PubMed=24760884; DOI=10.1128/JVI.00696-14; PMCID=PMC4054427
Stian Henriksen, Garth Daryl Tylden, Alexis Dumoulin, Biswa Nath Sharma, Hans H. Hirsch, Christine Hanssen Rinaldo;
The human fetal glial cell line SVG p12 contains infectious BK polyomavirus.
J. Virol. 88:7556-7568(2014)

PubMed=25288626; DOI=10.1128/JVI.01600-14; PMCID=PMC4248886
Michael W. Ferenczy, Eugene O. Major;
Contamination of SVG p12 cells with BK polyomavirus occurred after deposit in the American Type Culture Collection.
J. Virol. 88:12928-12929(2014)

PubMed=25288627; DOI=10.1128/JVI.02153-14; PMCID=PMC4248923
Christine Hanssen Rinaldo, Stian Henriksen, Garth Daryl Tylden, Hans H. Hirsch;
Reply to 'Contamination of SVG p12 cells with BK polyomavirus occurred after deposit in the American type culture collection'.
J. Virol. 88:12930-12930(2014)

Cross-references
Cell line collections (Providers) AddexBio; T0005008/4960
ATCC; CRL-8621
BCRC; 60371
Hysigen; TCH-C631
IZSLER; BS CL 200
Cell line databases/resources CLO; CLO_0009176
LINCS_LDP; LCL-2079
Anatomy/cell type resources BTO; BTO_0005184
Biological sample resources BioSample; SAMN03471204
Encyclopedic resources Wikidata; Q54971009
Entry history
Entry creation04-Apr-2012
Last entry update31-Mar-2026
Version number27